Farmacovigilância em unidade de saúde especializada em oncologia : projeto de implementação do serviço

Abstract

The accelerated growth in the antineoplastic drugs use may be traced by an increase in the number of cancer cases and a search for targeted therapy to the reduction of adverse drug reactions. However, the increase is not completely followed by well-structured and active oncovigilance in health clinics, demonstrating the importance of post-marketing active surveillance. In this sense, the objective of this study is to develop a project to implement a well-structured and active Pharmacovigilance service in an oncology health clinic through mechanisms such as application form adaptation and the strategies mapping to improve the quality of reporting by health professionals, as well as agility in detecting possible ADRs by the responsible inspection agencies. From this perspective, on the last year, exploratory study was developed with active literary search in national and international databases. Analyzing the data, the implementation of this service in clinics focusing on cancer treatment was not found, showing us the innovative idea of the current project. It is expected that the plan will be implemented in one year, adapted, and directed to the multi-professional team, under the management of a clinical pharmacist, through the use of the proposed instruments, thereby reducing ADRs under-reporting and improving the patient’s quality of life.