Perfil dos pacientes portadores de anemia falciforme acompanhados em um Hospital Universitário do Nordeste do Brasil – um estudo coorte

Abstract

Background: Sickle cell disease is a hemoglobinopathy of genetic transmission, of importance in the medical environment, due to its frequency and morbidity. To study the sociodemographic and clinical profile of patients with sickle cell disease, accompanied at the Pediatric Hematology Service of the University Hospital of the Federal University of Sergipe, contributes to a better care of this population. Objective: To study the sociodemographic and clinical profile of patients with sickle cell anemia at the Pediatric Hematology Service of HU- UFS. Methods: This is a historical cohort study, where sociodemographic parameters, clinical data, average of the last five laboratory tests and hospitalization frequency between 2012 and 2016, through the analysis of medical records. Results:.the mean age found was 13.7 years, composed of 41.5% of the males, 73% from the interior. The mean hospitalizations / year were 0.58 / year, 180 (66.7%) were submitted to blood transfusion, and 33 (18.3%) underwent chronic transfusion therapy. Cholelithiasis was the most frequent clinical complication with 51.6% of 134 patients. Conclusion: The study demonstrated a sociodemographic profile with a predominance of young people from the interior and male. The clinical profile showed a prevalence of cholecystitis, ventricular hypertrophy and cerebral vasculopathy. Ischemic ulcer, splenic sequestration and sexual dysfunction were the least prevalent.