Mortalidade por sepse e choque séptico em um hospital privado de Aracaju, SE

Abstract

Introduction: Sepsis is the dysfunction caused by an unregulated host response to infection. It is a public health concern and the main cause of death in intensive care units around the world, and studies in developing countries are scarce. Over the last years there is an international effort to reduce mortality, using protocols that direct treatment in the first hours of admission, and the applicability of these protocols rely on material and human resources. Sepsis mortality in Brazil is around 56%. Materials and methods: This study was observational, retrospective and cross- sectional. Data were collected in the hospital internal information database and patients in which protocol interventions could not be administered were excluded, because of their comorbities or because they were in palliative care. Results: In 2017 there were 455 cases of sepsis diagnosed in Hospital São Lucas, 434 (95,4%) of those were enrolled in the protocol, 113 (26%) of which presented with septic shock. 62 cases were excluded. Mortality as 6,2% (n = 23), all diagnosed with septic shock. Discussion: Mortality was lower than in studies that grouped severe sepsis and septic shock, 18,9% in the ProCESS study. However, the mortality in septic shock was similar to studies that observed only that, such as the ProMISe study. Conclusion: Protocol based treatment in sepsis improves its outcomes. Sepsis bundles help protocol adherence and should be known by decision-makers and those that work with sepsis treatment daily.