Avaliação do risco de fratura por meio do instrumento FRAX em pacientes com hepatite viral

Abstract

INTRODUCTION: Osteoporosis is a skeletal complication common, found in patients with DHC, usually asymptomatic and if not treated, can result in fractures and low quality of life. The bone densitometry (DXA) is the best parameter for assessment of bone mass; however, there are restrictions for determination of absolute risk of fractures. Fracture Risk Assessment (FRAX), an instrument developed by the University of Sheffield in collaboration with the World Health Organization (WHO), is the most used tool to incorporate the clinical risk factors, associated or not with the BMD to quantify the probability in 10 years of a patient presenting a hip fracture or a fracture greater. METERIALS AND METHODS: We selected 30 male patients, patients with viral hepatitis B or C, Child A the outpatient Division of Hepatology of Hospital Universitario of Universidade Federal de Sergipe and matched for sex, age, weight, height, BMI to assess the risk of osteoporotic fractures using the FRAX tool.RESULTS: The scores obtained by means of the instrument showed that none of the participants in this study presented risk ≥ 3% of osteoporotic fractures of the hip (GC = 0.21 ± 0.19 vs GH = 0.22 ± 0.18 p = 0.6) and/or > 20% of osteoporotic fractures greater (GC = 2.0 ± 0.70 vs GH = 2.1 ± 0.50 p = 0.2). CONCLUSIONS: Our data suggest that patients with chronic viral hepatitis B or C, Child A, without clinical risk factors for osteoporosis do not present a risk of osteoporotic fractures.