Doença pulmonar obstrutiva crônica em pacientes com suspeita de isquemia miocárdica

Abstract

It has been described the association between Chronic Obstructive Pulmonary Disease and cardiovascular disease. In the case of Cronic arterial disease, this association is probably due to similar risk factors and the systemic inflammation caused by COPD. In patients with stable COPD, the myocardial ischemia can remain without diagnostic and treatment e your consequences are not elucidated. This research aims to evaluate the COPC in patients with myocardial ischemia suspected. Methods: This is a cross-sectional study, which assessed 155 Smokers over 40 years. It was used the spirometry and exercise stress echocardiography (EPS). They were divided in Group one (G1) – patients with diagnostic of COPD (33% of the sample); Group two (G2) – without diagnostic of COPD (67% of the sample). It was used the Pearson's Chi-square test or Fisher exact test for categorical variables, while that for the continuous variables were evaluated by Student's t test. Results: The G1 showed higher frequency of chronic cough (p= 0.007), osteoporosis (p= 0.001) and cancer (p< 0.001). THE EPS, the E/e' ratio was higher in the Group G1 (11,12±4.73 vs. 9.81± 3.33) (p= 0.048) which denotes higher degree of diastolic dysfunction of the left ventricle (LV) in COPD. In relation to the diagnosis of myocardial ischemia, there was no difference between the groups (p = 0.552). Conclusion: Although the myocardial ischemia has not been more frequent in G1, this had more symptoms, comorbidities and higher degree of LV diastolic dysfunction, which may indicate a format silent CAD.