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Document Type:	Artigo
Title:	Trypanocidal activity of oxoaporphine and pyrimidine-β-carboline alkaloids from the branches of Annona foetida Mart. (Annonaceae)
Authors:	Costa, Emmanoel Vilaça Pinheiro, Maria Lúcia Belém Souza, Afonso Duarte Leão de Barison, Andersson Campos, Francinete Ramos Valdez, Rodrigo Hinojosa Ueda-Nakamura, Tânia Dias Filho, Benedito Prado Nakamura, Celso Vataru
Issue Date:	Nov-2011
Resumo :	Phytochemical investigation of the branches of Annona foetida Mart. led to isolation from the CH2Cl2 extract of four alkaloids: Atherospermidine (1), described for the first time in this species, liriodenine (2), O-methylmoschatoline (3), and annomontine (4). Their chemical structures were established on the basis of spectroscopic data from IR, MS, NMR (1D and 2D), and comparison with the literature. Compounds 2–4 showed potent trypanocidal effect when evaluated against epimastigote and trypomastigote forms of Trypanosoma cruzi.
Keywords:	Annonaceae Annona foetida Alkaloids Oxoaporphine alkaloids Pyrimidine-β-carboline alkaloids Trypanocidal activity
ISSN:	1420-3049
Is part of:	Molecules
Language:	eng
Publisher / Institution :	MDPI
Citation:	COSTA, E. V. et al. Trypanocidal activity of oxoaporphine and pyrimidine-β-carboline alkaloids from the branches of Annona foetida Mart. (Annonaceae). Molecules, Basel, v. 16, n. 11, p. 9714-9720, nov. 2011. Disponível em: https://www.mdpi.com/1420-3049/16/11/9714. Acesso em: 14 ago. 2025.
License:	Creative Commons Atribuição 3.0 Não Adaptada (CC BY 3.0)
URI:	https://ri.ufs.br/jspui/handle/riufs/22888
Appears in Collections:	DQI - Artigos de periódicos

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