Frequência de fatores de risco cardiovascular e de síndrome metabólica em mulheres portadoras de artrite reumatoide e lúpus eritematoso sistêmico

Abstract

OBJECTIVE: To analyze the frequency of Cardiovascular Risk (RCV) Factors and Metabolic Syndrome (MS) in patients with Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) of the Clinic of Rheumatology, Federal University of Sergipe. PATIENTS AND METHODS: Transversal and descriptive study. Participants were 150 women, grouped into three groups: GC (n = 50), GRA (n = 50) and GL (n = 50). The rating for the diagnosis of MS was the International Diabetes Federation (IDF), 2005. RESULTS: Presence of MS in 4 (8%), 30 (60%) and 25 (50%) of individuals GC, GRA and GL, respectively. CA (GC = 78,2 ± 6,4; GRA = 93,6 ± 12,7; GL = 87,9 ± 10,4 cm; p<0,0001), PAS (GC = 117,5 ± 7,2; GRA = 132,6 ± 19,3; GL = 120,4 ± 14,5 mmHg; p<0,0001), PAD (GC = 77,0 ± 7,3; GRA = 79,4 ± 14,2; GL = 77,7 ± 10,2 mmHg; p<0,053), HDL-colesterol (GC = 54,4 ± 6,3; GRA = 48,0 ± 15,6; GL = 48,3 ± 15,3 mg/dL; p<0,02), TG (GC = 114,7 ± 22,7; GRA = 166,7 ± 123,1; GL = 146,8 ± 77,8 mg/dL; p<0,01), glicemia (GC = 81,2 ± 5,1; GRA = 95,2 ± 58,2; GL = 80,8 ± 12,9 mg/dL; p<0,06). Patients of the GRA and GL diagnosed with MS had higher scores for RCV, the GRA had higher averages and frequencies, both the CVR factors as the overall risk score, compared to GL. CONCLUSION: Patients with RA and SLE have high frequency of SM, which is important for obtaining increased cardiovascular risk factors, and consequently cardiovascular disease.