Uso da fotobiomodulação a laser nas manifestações orais de uma paciente com timoma associado à Síndrome de SJÖGREN: relato de caso

Abstract

Thymomas are rare, slow-growing tumors that originate in the epithelial cells of the thymus and are notable for their association with autoimmune diseases such as Sjögren's Syndrome, which is an uncommon case and little discussed in the literature. The objective of this study was to report a case of thymoma associated with Sjögren's Syndrome in an oncology patient who attended the Laser Clinic of the Department of Dentistry of the Federal University of Sergipe (UFS), with mucositis and pseudomembranous candidiasis in the oral cavity, caused after the completion of radiotherapy and chemotherapy for thymoma, also associated with Sjögren's Syndrome. The therapeutic treatment adopted combined 7 sessions of Photobiomodulation and 3 sessions of Antimicrobial Photodynamic Therapy for the care of oral lesions, using the Laser Duo – MMOptics equipment (São Carlos, SP, Brazil, with a power of 100 mW and a spot area of 0.03 cm²). In photobiomodulation, infrared laser (wavelength of 808nm, Energy: 4J/point, time/point: 40s, Power density: 3.33W/cm2, Energy density = 133.3J/cm2) and red laser (wavelength of 660nm, Energy: 1J, time: 10s, total Energy - 20J/session, Total time - 200s, equivalent to a total time of 3.33 minutes/session) were applied to the dorsum of the tongue, hard palate, soft palate, lateral border of the tongue and left labial commissure for pain relief and modulation of the inflammatory response. To perform antimicrobial photodynamic therapy, a wavelength of 660nm was applied, Energy: 9J, time: 90s, total Energy - 36J/session, Total time - 360s, equivalent to a total time of 6 minutes/session, associated with 0.01% methylene blue gel, with a pre-irradiation time of 5 minutes, the application will be done in scanning mode, in the regions of the lateral edge of the tongue, dorsum of the tongue, left labial commissure and in the upper prosthetic piece. It was observed that the therapeutic protocol proved to be effective in resolving oral lesions, resulting in a significant improvement in the patient's quality of life.