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https://ri.ufs.br/jspui/handle/riufs/23302| Document Type: | Artigo |
| Title: | Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, state of Sergipe, Brazil |
| Authors: | Lemos, Lígia Mara Dolce de Rocha, Thaísa Fonseca Siqueira Conceição, Marcos Vinícius da Silva, Eduardo de Lemos Santos, Alessandro Henrique da Silva Gurgel, Ricardo Queiroz |
| Issue Date: | Dec-2012 |
| Resumo : | Introduction: The main route of human immunodeficiency virus (HIV) infection in children is from mother to child. The preventive measures established for the Aids Clinical Trial Group protocol 076 (ACTG 076) significantly reduces HIV vertical transmission rates. This study aims to evaluate the implementation of the ACTG 076 protocol in the maternity units of State of Sergipe, Brazilian northeast. Methods: This is a descriptive, retrospective study with a quantitative approach, with HIV positive women and children exposed, attending a Maternity reference for high-risk pregnancies. Data were obtained from patient records registered in the years 1994 to 2010. Results: Amongst the 110 pregnant women and exposed newborns, the ACTG 076 protocol was fully utilized in only 31.8% of the participants. During the prenatal period, zidovudine (ZDV) was taken by 79.1% of the pregnant women. Only 49.1% of HIV seropositive patients used ZDV during delivery. Two (1.8%) children were considered infected and 50 (45.5%) do not have a conclusive diagnosis to date. Conclusions: There were significant deficiencies in the prevention of mother-to-child transmission of HIV, including lack of compliance with the three phases of the ACTG 076 protocol; inadequacies in prenatal care; inappropriate mode of delivery and lack of adequate follow up of exposed children. |
| Keywords: | HIV Vertical transmission of infectious disease Zidovudine Post-exposure prophylaxis |
| ISSN: | 1678-9849 |
| Is part of: | Revista da Sociedade Brasileira de Medicina Tropical |
| Language: | por |
| Publisher / Institution : | Sociedade Brasileira de Medicina Tropical - SBMT |
| Citation: | LEMOS, L. M. D. et al. Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, state of Sergipe, Brazil, Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 46, n. 6, p. 682-686, nov./dez. 2012. Disponível em: https://www.scielo.br/j/rsbmt/a/RfTHVPBrsv3M3MhcKFvVPTs/?lang=en. Acesso em: 26 set. 2025. |
| License: | Creative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0) |
| URI: | https://ri.ufs.br/jspui/handle/riufs/23302 |
| Appears in Collections: | DEN - Artigos de periódicos PPGCS - Artigos de periódicos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| PreventiveMeasuresMotherChildTransmissionHIV.pdf | 641,13 kB | Adobe PDF |  View/Open |
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