Eficácia da Calêndula officinalis L. (Asteraceae) na gengivite e do própolis na hipersensibilidade dentinária: análises da evidência científica

Abstract

The use of natural products is widely studied in dentistry, due to several advantages, such as the great diversity of medicinal plants found in Brazil, biological activity, lower side effects, lower bacterial resistance, in addition to enhancing the local effect and avoiding systemic toxicity. Therefore, the objective of this thesis was to evaluate the effectiveness of two natural products, a plant species and a product derived from bees, in dental pathologies through an analysis of scientific evidence. The specific objectives evaluated the effectiveness of Calendula officinalis L. in gingivitis and propolis in dentin hypersensitivity, through two systematic reviews. To facilitate understanding of the data and because these are two different products for different dental pathologies, the results were divided into chapter format. The second chapter shows the first systematic review that evaluated the effectiveness of Calendula officinalis L. in the treatment of gingivitis, through a search carried out in the databases Pubmed, Scopus, Web of Science, Lilacs, Embase, aiming to identify clinical trials and four were included studies, for data extraction, and it can be observed that Calendula officinalis has beneficial effects in the treatment of gingivitis, due to its anti-inflammatory, antioxidant and immunomodulatory properties and may even be a future option in the treatment of gingivitis, however new studies are encouraged . The third chapter shows the second systematic review that evaluated the effectiveness of propolis in reducing dentin hypersensitivity, through a search carried out in the databases Pubmed, Scopus, Web of Science, Lilacs, Embase, Brazilian Library in Dentistry (BBO), and Cochrane Library, six studies were included for data extraction and it was observed that propolis is an effective, safe method for reducing dentin hypersensitivity. Therefore, the completion of this thesis shows that natural products present promising results in dental pathologies, in general. Scientific evidence shows effective results from the use of Calendula officinalis in the treatment of gingivitis and propolis in reducing dentin hypersensitivity. From this perspective, this thesis was based on encouraging the applicability of two natural products in dental pathologies, as new therapeutic options, as well as developing studies to produce new formulations and strengthening scientific evidence for clinical decision making.