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https://ri.ufs.br/jspui/handle/riufs/23547| Tipo de Documento: | Artigo |
| Título : | Ent-kaurane diterpenoids and other constituents from the stem of Xylopia laevigata (Annonaceae) |
| Autor : | Silva, Dayanne Meneses Costa, Emmanoel Vilaça Nogueira, Paulo Cesar de Lima Moraes, Valéria Regina de Souza Cavalcanti, Sócrates Cabral de Holanda Salvador, Marcos José Ribeiro, Luis Henrique Gonzaga Gadelha, Fernanda Ramos Barison, Andersson Ferreira, Antonio Gilberto |
| Fecha de publicación : | 2012 |
| Resumen: | Phytochemical investigation of the hexane extract from the stem of Xylopia laevigata led to the isolation of the ent-kaurane diterpenoids, ent-kaur-16-en-19-oic acid, 4-epi-kaurenic acid, ent-16b-hydroxy-17-acetoxy-kauran-19-al, ent-3b-hydroxy-kaur-16- en-19-oic acid, and ent-16b,17-dihydroxy-kauran-19-oic acid, as well as spathulenol and a mixture of b-sitosterol, stigmasterol and campesterol. The identification of the compounds was performed on the basis of spectrometric methods including GC-MS, IR, and 1D and 2D NMR. Potent larvicidal activity against Aedes aegypti larvae with LC50 of 62.7 mg mL-1 was found for ent-3b-hydroxykaur-16-en-19-oic acid. This compound also showed significant antifungal activity against Candida glabrata and Candida dubliniensis with MIC values of 62.5 mg mL-1. |
| Palabras clave : | Xylopia laevigata Ent-kaurane-diterpenes Larvicidal properties Antifungal properties |
| ISSN : | 1678-7064 |
| Es parte de: | Química Nova |
| Idioma : | eng |
| Institución / Editorial : | Sociedade Brasileira de Química |
| Citación : | SILVA, D. M. et al. Ent-kaurane diterpenoids and other constituents from the stem of Xylopia laevigata (Annonaceae). Química Nova, São Paulo, v. 35, n. 8, p. 1570-1576, 2012. Disponível em: https://www.scielo.br/j/qn/a/kp4NVBgm9xQWGRXBtRBn4Hj/?lang=en. Acesso em: 16 out. 2025. |
| License: | Creative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0) |
| URI : | https://ri.ufs.br/jspui/handle/riufs/23547 |
| Aparece en las colecciones: | DFA - Artigos de periódicos DQI - Artigos de periódicos |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| EntKauraneDiterpenoidsCostituentsStemXylopiaLaevigata.pdf | 1,05 MB | Adobe PDF |  Visualizar/Abrir |
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