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https://ri.ufs.br/jspui/handle/riufs/23554| Document Type: | Artigo |
| Title: | Caavuranamide, a novel steroidal alkaloid from the ripe fruits of Solanum caavurana Vell. (Solanaceae) |
| Authors: | Vaz, Nelissa Pacheco Costa, Emmanoel Vilaça Santos, Érica Luiz dos Mikich, Sandra Bos Marques, Francisco de Assis Braga, Raquel Marques Delarmelina, Camila Duarte, Marta Cristina Teixeira Ruiz, Ana Lúcia Tasca Gois Souza, Vanessa Helena da Silva Carvalho, João Ernesto de Maia, Beatriz Helena Lameiro de Noronha Sales |
| Issue Date: | 2012 |
| Resumo : | Phytochemical investigation of the ripe fruits of Solanum caavurana Vell. (Solanaceae) afforded a novel steroidal alkaloid with spirosolane-type skeleton, named as caavuranamide, together with the alkaloids 4-tomatiden-3-one and 5α-tomatidan-3-one. Their structures were elucidated on the basis of spectroscopic methods. The antiproliferative and antimicrobial activities for the ethanolic extract, sub-fractions obtained from partition and acid-base treatment were also evaluated. Caavuranamide showed antibacterial activity similar to the chloramphenicol positive control against Rhodococcus equi. |
| Abstract: | A investigação fitoquímica dos frutos maduros de Solanum caavurana Vell. (Solanaceae) forneceu um novo alcaloide esteroidal do tipo espirosolano, caavuranamida, juntamente com os alcaloides 4-tomatiden-3-ona e 5α-tomatidan-3-ona. Suas estruturas foram elucidadas através de métodos espectroscópicos. As atividades antiproliferativa e antimicrobiana para o extrato etanólico e subfrações provenientes de partição e de extração ácido-base foram investigadas. A caavuranamida apresentou atividade antibacteriana similar ao controle positivo cloranfenicol contra Rhodococcus equi. |
| Keywords: | Solanum caavurana Solanaceae Caavuranamide Steroidal alkaloids Spirosolane Caavuranamida Alcaloide esteroidal |
| ISSN: | 1678-4790 |
| Is part of: | Journal of the Brazilian Chemical Society |
| Language: | eng |
| Publisher / Institution : | Sociedade Brasileira de Química |
| Citation: | VAZ, N. P. et al. Caavuranamide, a novel steroidal alkaloid from the ripe fruits of Solanum caavurana Vell. (Solanaceae). Journal of the Brazilian Chemical Society, Campinas, v. 23, n. 2, p. 361-366, 2012. Disponível em: https://www.scielo.br/j/jbchs/a/FRshgD8c4xcSwdGLvf6bCbF/?lang=en. Acesso em: 16 out. 2025 |
| License: | Creative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0) |
| URI: | https://ri.ufs.br/jspui/handle/riufs/23554 |
| Appears in Collections: | DQI - Artigos de periódicos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| CaavuranamideNovelSteroidalAlkaloid.pdf | 990,21 kB | Adobe PDF |  View/Open |
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