Avaliação da genotoxicidade e citotoxicidade dos Raios X no epitélio da mucosa oral de adultos submetidos à tomografia computadorizada de feixe cônico parcial

Abstract

Objectives: To evaluate the genotoxicity and cytotoxicity of X-rays in the oral mucosa epithelium of adult patients submitted to partial conical beam computed tomography. Methods: A total of 15 healthy adults undergoing CBCT were included. The material was collected in two stages: immediately before and ten days after the CBCT, by means of a smear in the vestibular fundus of the oral mucosa. The material was processed and the blades were prepared for the microscopic analysis. After that, a descriptive and inferential statistical analysis was performed at a significance level of 5%. Results: With regard to frequency (%) of MNC (mutagenicity) there was no statistical difference between the different collection times before and after the partial CBCTs (p = 0.088). Regarding the other alterations evaluated (cytotoxicity) there was also no statistically significant difference in partial acquisition (p = 0.496). Conclusion: From these data we conclude that the partial CBCT does not induce genotoxic and cytotoxic effects, requiring further studies that make this comparison possible for a better understanding.