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Document Type:	Artigo
Title:	Underreporting of Dengue-4 in Brazil due to low sensitivity of the NS1 Ag test in routine control programs
Authors:	Sea, Vanessa Ramos Faria Cruz, Ana Cecília Ribeiro Gurgel, Ricardo Queiroz Nunes, Bruno Tardelli Diniz Silva, Eliana Vieira Pinto Dolabella, Silvio Santana Santos, Roseli La Corte dos
Issue Date:	May-2013
Resumo :	We have identified fifty-eight samples that were positive for Dengue-4 among 119 samples with negative diagnoses for dengue via the PlateliaTM dengue NS1 Ag in Aracaju, State of Sergipe, Brazil. We determined that the low sensitivity of the NS1 Ag test could be related to secondary dengue infections in the studied population. Therefore, we concluded that the sensitivity and specificity of the PlateliaTM dengue NS1 Ag test as a screening method for monitoring circulating dengue serotypes must be reevaluated. In addition, regional endo-epidemic profiles should also be considered due to the prevalence of secondary responses.
Keywords:	Dengue NS1 Ag test Platelia
ISSN:	1932-6203
Is part of:	PloS One
Language:	eng
Publisher / Institution :	Public Library of Science
Citation:	SEA, V. R. F. et al. Underreporting of Dengue-4 in Brazil due to low sensitivity of the NS1 Ag test in routine control programs. PloS one, San Francisco, v. 8, n. 5, e64056, maio 2013. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064056. Acesso em: 5 jan. 2026.
License:	Creative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0)
URI:	https://ri.ufs.br/jspui/handle/riufs/24117
Appears in Collections:	DEN - Artigos de periódicos DME - Artigos de periódicos

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