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https://ri.ufs.br/jspui/handle/riufs/24564| Document Type: | Artigo |
| Title: | Evaluation of the anti-Inflammatory and antinociceptive effects of the essential oil from leaves of Xylopia laevigata in experimental models |
| Authors: | Queiroz, João Carlos C. Antoniolli, Ângelo Roberto Quintans Júnior, Lucindo José Brito, Renan Guedes de Barreto, Rosana de Souza Siqueira Costa, Emmanoel Vilaça Silva, Thanany Brasil da Prata, Ana Paula Nascimento de Lucca Júnior, Waldecy Almeida, Jackson Roberto Guedes da Silva Lima, Julianeli Tolentino de Quintans, Jullyana de Souza Siqueira |
| Issue Date: | 2014 |
| Resumo : | Xylopia laevigata (Annonaceae) is a medicinal plant used in folk medicine to treat pain and inflammation. Thus, we investigated the possible antioxidant, antinociceptive, and anti-inflammatory effects of X. laevigata leaf essential oil (EOX) in animal models.Our EOX sample showed the presence of y-muurolene (17.78%), &-cadinene (12.23%), bicyclogermacrene (7.77%), and a-copaene(7.17%) as main compounds. EOX presented a strong antioxidant potential according to the DPPH, TBARS, and nitrite productiontests. Additionally, pretreatment with EOX, in mice, also significantly produced (p < 0.05 or p < 0.001) antinociceptive effect byreduction of nociceptive behavior (in formalin and writhing tests). The EOX showed c-Fos label in the olfactory bulb, piriformcortex, and periaqueductal gray. Acute administration of EOX exhibited a significant (p < 0.01 or p < 0.001) anti-inflammatoryprofile in the carrageenan-induced peritonitis and by the carrageenan-induced hindpaw edema tests in mice. Our results provideevidence for the use of X. laevigata by traditional medicine practitioners in the management of pain and inflammatory disorders. |
| Keywords: | Xylopia laevigata Anti-inflammatory effects Essential oil |
| ISSN: | 1537-744X |
| Language: | por |
| Citation: | QUEIROZ, J. C. C. et al. Evaluation of the anti-Inflammatory and antinociceptive effects of the essential oil from leaves of Xylopia laevigata in experimental models. The Scientific World Journal, New York, n. 1, 2014. Disponível em: https://onlinelibrary.wiley.com/doi/10.1155/2014/816450. Acesso em: 10 fev. 2026. |
| License: | Creative Commons Atribuição 3.0 Não Adaptada (CC BY 3.0) |
| URI: | https://ri.ufs.br/jspui/handle/riufs/24564 |
| Appears in Collections: | DFS - Artigos de periódicos DQI - Artigos de periódicos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| AntinociceptiveEffectsEssentialOilXylopiaLaevigata.pdf | 2,78 MB | Adobe PDF |  View/Open |
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