1. Repositório Institucional da Universidade Federal de Sergipe - RI/UFS
2. PRODUÇÃO CIENTÍFICA
3. PROBP - Programa de Pós-Graduação em Biologia Parasitária (Produção Científica)
4. PROBP - Artigos de periódicos

Tipo de Documento:	Artigo
Título:	Diarrhea incidence and intestinal infections among rotavirus vaccinated infants from a poor area in Brazil: a spatial analysis
Autor(es):	Santos, Claudimary Bispo Araújo, Karina Conceição Gomes Machado de Jardim-Botelho, Anne Santos, Márcio Bezerra Rodrigues, Alda Dolabella, Silvio Santana Gurgel, Ricardo Queiroz
Data do documento:	2014
Resumo:	Background: Acute diarrhea is the second leading cause of mortality among children under 5 years of age in developing countries. The pathogen most strongly associated with diarrhea is rotavirus followed by enteric pathogens such as bacteria, helminthes and protozoan. Adequate sanitation and water supply contribute to decrease acute diarrhea incidence of most etiologic agents, although vaccination remains the most important intervention to control rotavirus acute diarrhea. This study aimed to describe environmental conditions and analyze spatially the acute diarrhea and intestinal infection among rotavirus vaccinated infants from Laranjeiras-Sergipe, Brazil. Methods: Children were enrolled between 2 and 11 months of age and followed through 12 months. Demographic, socioeconomic and environmental data were obtained from a questionnaire, and immunization data were obtained from children vaccination card. Children stool samples were collected each month in order to run laboratory analyses. The household spatial localization was obtained by using a Global Positioning System (GPS). Spatial analysis was performed using the TerraView computer program and Kernel intensity estimation. Results: A total of 1,113 stool samples were collected with 80 being diarrhea associated. Diarrhea incidence rate was 0.5 ± 1.0 episodes/child/year. The overall infection rates by Ascaris lumbricoides, Endolimax nana, Giardia lamblia and rotavirus were 5.1%, 3.0%, 0.9% and 2.6%, respectively. 3.8% of diarrhea-associated stool samples were positive for rotavirus and 11.3% were positive for helminths and protozoans. There were some changes on spatial distribution of intestinal infections and diarrhea episodes along the four trimesters evaluated. Conclusions: The studied infants live equally in precarious conditions of sanitation which probably explain the significant rates of parasitic infections appearing in early life. The low acute diarrhea incidence in the studied rotavirus vaccinated population and the low number of symptomatic rotavirus infection may indicate vaccination efficacy to prevent acute diarrhea among young children in a poor environmental sanitary setting.
Palavras-chave:	Spatial analysis Acute diarrhea Environmental conditions Intestinal infections Rotavirus
ISSN:	1471-2458
Parte de :	BMC public health
Idioma:	eng
Instituição/Editora:	BioMed Central
Citação:	SANTOS, C. B. et al. Diarrhea incidence and intestinal infections among rotavirus vaccinated infants from a poor area in Brazil: a spatial analysis. BMC public health, London, v. 14, n. 399, 2014. Disponível em: https://link.springer.com/article/10.1186/1471-2458-14-399. Acesso em: 12 fev. 2026.
Licença:	Creative Commons Atribuição 2.0 Genérica (CC BY 2.0)
Identificador:	https://doi.org/10.1186/1471-2458-14-399
URI:	https://ri.ufs.br/jspui/handle/riufs/24581
Aparece nas coleções:	DME - Artigos de periódicos DMO - Artigos de periódicos PPGCS - Artigos de periódicos PROBP - Artigos de periódicos

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