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https://ri.ufs.br/jspui/handle/riufs/24642| Document Type: | Artigo |
| Title: | Antioxidant activity and mechanisms of action of natural compounds isolated from lichens: a systematic review |
| Authors: | White, Pollyanna Alves Secundo Oliveira, Rita de Cássia Meneses Oliveira, Aldeidia Pereira de Serafini, Mairim Russo Araújo, Adriano Antunes de Souza Gelain, Daniel Pens Moreira, José Cláudio Fonseca Almeida, Jackson Roberto Guedes da Silva Quintans, Jullyana de Souza Siqueira Quintans Júnior, Lucindo José Santos, Márcio Roberto Viana dos |
| Issue Date: | 2014 |
| Resumo : | Chronic diseases such as cancer, diabetes, neurodegenerative and cardiovascular diseases are characterized by an enhanced state of oxidative stress, which may result from the overproduction of reactive species and/or a decrease in antioxidant defenses. The search for new chemical entities with antioxidant profile is still thus an emerging field on ongoing interest. Due to the lack of reviews concerning the antioxidant activity of lichen-derived natural compounds, we performed a review of the antioxidant potential and mechanisms of action of natural compounds isolated from lichens. The search terms “lichens”, “antioxidants” and “antioxidant response elements” were used to retrieve articles in LILACS, PubMed and Web of Science published until February 2014. From a total of 319 articles surveyed, 32 met the established inclusion and exclusion criteria. It was observed that the most common isolated compound studied was usnic acid, cited in 14 out of the 32 articles. The most often described antioxidant assays for the study of in vitro antioxidant activity were mainly DPPH, LPO and SOD. The most suggested mechanisms of action were scavenging of reactive species, enzymatic activation and inhibition of iNOS. Thus, compounds isolated from lichens are possible candidates for the management of oxidative stress, and may be useful in the treatment of chronic diseases. |
| Keywords: | Lichens Antioxidants Antioxidant response elements DPPH Cancer Chronic disease |
| ISSN: | 1420-3049 |
| Is part of: | Molecules |
| Language: | eng |
| Publisher / Institution : | MDPI |
| Citation: | WHITE, P. A. S. et al. Antioxidant activity and mechanisms of action of natural compounds isolated from lichens: a systematic review. Molecules, Basel, v. 19, n. 9, p. 14496–14527, 2014. Disponível em: https://www.mdpi.com/1420-3049/19/9/14496. Acesso em: 25 fev. 2026. |
| License: | Creative Commons Atribuição 3.0 Não Adaptada (CC BY 3.0) |
| Identifier: | https://doi.org/10.3390/molecules190914496 |
| URI: | https://ri.ufs.br/jspui/handle/riufs/24642 |
| Appears in Collections: | DFA - Artigos de periódicos DFAL - Artigos de periódicos DFS - Artigos de periódicos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| AntioxidantActivityNaturalCompoundsLichens.pdf | 837,91 kB | Adobe PDF |  View/Open |
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