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4. DECO - Artigos de periódicos

Tipo de Documento:	Artigo
Título :	Prevalence of type-specific HPV among female university students from northern Brazil
Autor :	Vieira, Rodrigo Covre Monteiro, Jeniffer do Socorro Valente Manso, Estéfane Primo Santos, Maria Renata Mendonça dos Tsutsumi, Mihoko Yamamoto Ishikawa, Edna Aoba Yassui Ferrari, Stephen Francis Lima, Karla Valéria Batista Sousa, Maísa Silva de
Fecha de publicación :	2015
Resumen:	Background: Human papillomavirus (HPV) infection is associated with cervical cancer, the most frequent cancer in women from northern Brazil. Assessment of the short-term impact of HPV vaccination depends on the availability of data on the prevalence of type-specific HPV in young women in the pre-immunization period, although these data are currently unavailable for the study region. The aim of this study was to estimate the distribution of all mucosal HPV genotypes, including low- and high-risk HPV types, in unvaccinated college students from northern Brazil. Findings: Specimens were collected from 265 university students during routine cervical cancer screening. The HPV DNA was assessed by Polymerase Chain Reaction and positive samples were genotyped by Restriction Fragment Length Polymorphism. Most students (85.7 %) had normal cytological results. The prevalence of HPV was 25.3 % (67/265), with a high frequency of multiple infections and non-vaccine high-risk HPV genotypes. The most prevalent type was HPV-61 (5.3 %), followed by types 82, 16, 59, and 6. Multiple infections were associated with high-risk and possibly high-risk HPVs. Conclusions: We demonstrated a high prevalence of HPV infection in university students from northern Brazil. Vaccine high-risk types were relatively rare, emphasizing the predominance of carcinogenic genotypes that are not prevented by the currently available vaccines. Our study highlights the need to reinforce cytological screening in women from northern Brazil, and promote the early diagnosis and treatment of the precancerous lesions associated with cervical cancer.
Palabras clave :	Human papillomavirus Prevalence HPV vaccine impact Genotype distribution
ISSN :	1750-9378
Es parte de:	Infectious Agents and Cancer
Idioma :	eng
Institución / Editorial :	BioMed Central
Citación :	VIEIRA, R. C. et al. Prevalence of type-specific HPV among female university students from northern Brazil. Infectious Agents and Cancer, London, v. 10, n. 21, 2015. Disponível em: https://link.springer.com/article/10.1186/s13027-015-0017-x. Acesso em: 18 maio 2026.
License:	Creative Commons Atribuição 4.0 Internacional (CC BY 4.0)
Identificador:	https://doi.org/10.1186/s13027-015-0017-x
URI :	https://ri.ufs.br/jspui/handle/riufs/25152
Aparece en las colecciones:	DECO - Artigos de periódicos

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