Please use this identifier to cite or link to this item: https://ri.ufs.br/jspui/handle/riufs/25572
Document Type: Artigo
Title: Fluoride-releasing materials to prevent white spot lesions around orthodontic brackets: a systematic review
Authors: Nascimento, Patrícia Layane de Menezes Macêdo
Fernandes, Micaelle Tenório Guedes
Figueiredo, Fabricio Eneas Diniz de
Faria e Silva, André Luis
Issue Date: 2016
Resumo : The relation between orthodontic fixed appliances use and enamel demineralization is well established. Different preventive approaches have been suggested to this problem, but controversy remains about which is the best. The aim of this study was to perform a systematic review of clinical trials that investigated the effectiveness of materials containing fluorides to lute brackets or cover the bonding interface in order to inhibit the development and progression of white spot lesions. The null hypothesis was that fluoride materials do not affect the incidence of white spot lesions around brackets. A MEDLINE search was conducted for randomized clinical trials evaluating the development of white spot lesions in patients using fixed orthodontic appliances, followed by meta-analysis comparing the results for patients for whom dental materials containing fluorides were used (experimental group) to those for whom these materials were not used (control group). The pooled relative risk of developing white spot lesions for the experimental group was 0.42 (95% confidence interval: 0.25 to 0.72); hence, when fluoride-releasing materials are used, the patient has 58% less risk of white spot lesion development. Regarding white spot lesion extent, the pooled mean difference between the experimental and control groups was not statistically significant (-0.12; 95% confidence interval: –0.29 to 0.04). In conclusion, the results of the present systematic review suggest that fluoride-releasing materials can reduce the risk of white spot lesions around brackets. However, when white spot lesions had already occurred, there is no evidence that fluoride-releasing materials reduce the extent of these lesions.
Keywords: Orthodontic brackets
Dental enamel solubility
Cariostatic agents
Meta-analyses
Is part of: Brazilian Dental Journal
Language: eng
Publisher / Institution : Fundação Odontológica de Ribeirão Preto
Citation: NASCIMENTO, P. L. M. M. et al. Fluoride-releasing materials to prevent white spot lesions around orthodontic brackets: a systematic review. Brazilian Dental Journal, Ribeirão Preto, v. 27, n. 1, p. 101–107, 2016. Disponível em: https://www.scielo.br/j/bdj/a/bDzgN7PMzmRhdKvM4v6VhHb/?lang=en. Acesso em: 16 jul. 2026.
License: Creative Commons Atribuição 4.0 Internacional (CC BY 4.0)
Identifier: https://doi.org/10.1590/0103-6440201600482
URI: https://ri.ufs.br/jspui/handle/riufs/25572
Appears in Collections:DOD - Artigos de periódicos
PPGCS - Artigos de periódicos

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