Avaliação do efeito da intervenção farmacêutica no controle da glicemia de pacientes ambulatoriais portadores do diabetes mellitus tipo 2

Abstract

Diabetes mellitus (DM) is a syndrome of multiple etiologies resulting from lack of insulin and / or the inability of insulin properly exercise its effects. It is considered the world, a public health problem by the position it occupies with high epidemiological incidence and prevalence, besides causing macrovascular and microvascular complications. The DM has two main forms, type 1 (DM1), which appears mostly in childhood or adolescence and type 2 (DM2), the most frequent, accounting for 85% to 90% of cases, usually of insidious onset, especially after 40 years of age, affecting obese individuals in 90% of the time. Cardiovascular diseases (CVD) are responsible for approximately 52% of deaths of patients with DM. The strategy of prevention of these chronic complications essentially depend on the adequate control of blood glucose and other comorbidities, including dyslipidemia and hypertension (SAH). This ivestigação was conducted to evaluate the effect of pharmaceutical intervention on glycemic control in outpatients suffering from DM2.Trata is a longitudinal study with intervention, using 100 subjects during query consecutively diagnosed with DM2 in private clinic endocrinology from May 2011 to February 2012. All patients answered a questionnaire and underwent pharmaceutical intervention, conducted by the researcher. After this intervention, there was a significant reduction of 45% CI 95% in A1C levels. Thus, there was still improvement in outcomes among women (69%) (p = 0.01) and the following parameters: fasting glucose (p = 0.000), frequency of exercise (p = 0.0001), adoption of low-calorie diet (p = 0.0001), adherence to drug therapy (p = 0.024) and BMI (p = 0.012).