Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorAntoniolli, Ângelo Roberto-
dc.contributor.authorMatos, Anne Caroline Carvalho-
dc.contributor.authorTeixeira-Silva, Flávia-
dc.contributor.authorGoes, Tiago C.-
dc.contributor.authorQuintans-Júnior, Lucindo José-
dc.contributor.authorAlbuquerque Júnior, Ricardo Luiz Cavalcanti de-
dc.contributor.authorBonjardim, Leonardo Rigoldi-
dc.identifier.citationMATOS, A. C. C. et al. Trait anxiety affects the orofacial nociceptive response in rats. Biological Research, v. 44, n. 4, p. 357-361, 2007. Disponível em: <>. Acesso em: 17 set. 2014.pt_BR
dc.description.abstractThe aims of the present study were to assess the influence of: a) trait anxiety on orofacial pain; and b) orofacial pain on state anxiety. Forty-four rats were initially exposed to the free-exploratory paradigm for the evaluation of their anxiety profiles. In accordance to the parameter "Percentage of time in the novel side", the animals were considered as presenting high or low levels of trait anxiety when presenting values below the 1st quartile, or above the 3rd quartile, respectively. A week later, formalin-1.5% was injected into the upper lip of each animal. The behavioural nociceptive response, characterized by increased orofacial rubbing (OR), was quantified for 30 minutes, as follows: Total time OR (0-30 minutes: total pain), 1st phase OR (0-6 minutes: neurogenic pain), and 2nd phase OR (12-30 minutes: inflammatory pain). Immediately after this test, but still under the effect of formalin, the rats were submitted to the Elevated Plus-maze test (EPM). The results showed that the high trait anxiety individuals presented higher frequency of OR than the low trait anxiety ones, except during the neurogenic pain period. However, no correlation was found between OR frequency and levels of state anxiety presented on the EPM. In conclusion, the animals presenting higher anxiety profiles were the most susceptible to orofacial pain, nevertheless, orofacial pain did not influence state anxiety.pt_BR
dc.publisherSociedad de Biología de Chilept_BR
dc.subjectTraço de ansiedadept_BR
dc.subjectTeste de formalinapt_BR
dc.subjectNocicepção orofacialpt_BR
dc.subjectEstado ansiedadept_BR
dc.titleTrait anxiety affects the orofacial nociceptive response in ratspt_BR
dc.identifier.licenseCreative Commons Attribution Licensept_BR
Appears in Collections:DFS - Artigos de periódicos

Files in This Item:
File Description SizeFormat 
TraitAnxietyAffects.pdf246,96 kBAdobe PDFThumbnail

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.