Evolução epidemiológica dos tumores primários do sistema nervoso central no Estado de Sergipe

Abstract

Central Nervous System (CNS) tumors are an extensive and heterogeneous group of entities. In addition to the significant morbimortality of these neoplasms, studies suggest an ascending pattern in their incidence. The study aims to evaluate the epidemiological evolution of primary CNS tumors diagnosed in the state of Sergipe between 2000 to 2010 and 2010 to 2018. Histopathological and immunohistochemical reports of primary CNS tumors diagnosed between 2010 and 2018 in the state of Sergipe were evaluated. The data collected was compared to results of a similar study conducted in the Sergipe population between 2000 and 2010. A total of 861 primary CNS tumors were found. Gliomas presented the highest prevalence (32.3%; n = 278). The female sex was the most affected (56.9%, n = 490). The cerebral location was the most frequent (50.8%; n = 437). The observed neoplasms prevailed in the age range of 45 to 54 years (20.4%; n = 176). Grade I tumors corresponded to 43.9% (n = 378) of the cases. It was evidenced an ascending pattern in the prevalence of these tumors between the years 2010 and 2018, showing a strong relation with the population increase at the same time (p = 0.006). Compared to the previous decade, there was an absolute increase in the number of cases, without statistical significance (p = 0.762). An absolute increase in the number of cases between the two decades evaluated was observed. The upward pattern of tumors between 2010 and 2018 appears to be related to the population increase.