Anomalias congênitas do Sistema Nervoso Central em Sergipe: análise do período 2001 a 2015

Abstract

Objective. To evaluate the profile of Congenital Anomalies of the Central Nervous System (CNS) in the state of Sergipe, from 2001 to 2015. Method. A descriptive, retrospective study was carried out. The CNS cases were from the following sources: Live Birth Information Systems (SINASC) and Mortality (SIM). The data were analyzed by the Tabwin program. The prevalence of CNS disease according to the year and type of malformation was evaluated. Infant mortality and CNS components were also evaluated, in addition to fetal and perinatal mortality. Result. Fetal mortality coefficients (2.0 per 10,000 births), perinatal (5.5 per 10,000 births), early neonatal (3.6 per 10,000 live births - NV), neonatal (4.4 per 10,000 NV) (5.7 per 10,000 NV) were stable in the period 2001-2015, but there was an increase in the CNS prevalence of CNS of 9.8 in the period from 2001 to 2014, to 34.1 per 10,000 NV in 2015. Anencephaly was responsible for the majority of fetal (76.9%) and infant (49.4%) deaths. There was an increase in the prevalence of CNS in the year 2015, with microcephaly being the main reason for this increase (from 0.42 per 10,000 NV of 2001 and 2014 to 23.2 per 10,000 NV in 2015). Conclusion. CNS are important cause of morbidity and mortality in children in Sergipe, and there is a need for the application of prophylactic measures for those that are preventable due to the exposure of the Zika virus in pregnancy.