Caracterização clínica dos pacientes com hemoglobinopatia atendidos no Hemocentro de Sergipe

Abstract

Objective: To describe the clinical characteristics of patients with hemoglobinopathies at the Blood Center of Sergipe. Methods: In this cross-sectional study, clinical data were collected from patients with hemoglobinopathies by reading the medical records. Descriptive statistics and variable analysis were performed using the ANOVA test for comparison of means and Fisher's exact test for association, using a significance level of p<0.05. Results: Data were collected from 96 patients. The main hemoglobinopathy found was SS (85.4%), followed by SC (11.5%) and β-thalassemia (3.1%). The main complication was hyperferritinemia (50.7%), which had a direct relationship with blood transfusion (p=0.039) and patients with more complications had an older age (p=0.026). Hemotransfusion was required in 71.9% of the patients, whereas hydroxyurea and deserafirox in 40.6% and 13.5%, respectively. Conclusion: The main hemoglobinopathy found was SS, the main complication was hyperferritinemia and the main treatment was hemotransfusion.