Coinfecção entre candidíase mucocutânea e micobacterioses: relato de uma família afetada

Abstract

The article aims to report a family of chronic mucocutaneous candidiasis and co-infection by mycobacteria (M. tuberculosis and M. leprae), as well as associating with existing data in the literature. The index case is a female patient 36 years old, with chronic mucocutaneous candidiasis (CMC) since childhood, mainly in the oropharynx and nails. Treatments were performed, including admissions. At age 31 she was diagnosed with Lepromatous leprosy and at 34 was diagnosed with tuberculosis. This patient has a 10 years old daughter that also since 3 months old has pictures of candidiasis in nails, lips and oral cavity and which has so far showed no mycobacterial infections. She also have a 40 years-old sister that does not present fungal infection, but was also diagnosed with leprosy. This family report confirms new data in the literature on genetic and immunologic relationship between chronic mucocutaneous candidiasis and Mycobacteriosis.