Positividade aos sinais de alerta para imunodeficiências primárias: prevalência na enfermaria pediátrica em um hospital de ensino

Abstract

Primary immunodeficiencies (PIDs) correspond to a group of heterogeneous diseases that affect the immune system's ability to combat pathogens. In the pediatric population, PIDs can signi ficantly compromise quality of life and are often associated with recurrent infections. Thus, the study evaluated the prevalence of warning signs for primary immunodeficiencies among pedi atric patients hospitalized in a hospital. With a cross-sectional and quantitative approach, the research was conducted in the municipality of Lagarto, in the interior of the state of Sergipe, northeastern Brazil, through the application of questionnaires to children—or their guardians—hospitalized at the Lagarto University Hospital from September 2023 to August 2024. The collected data were tabulated in Microsoft Excel XP® version 2013 and imported into the Sta tistical Package for the Social Sciences (IBM SPSS) for Windows XP®, version 22, for pro cessing and analysis. The prevalence of positive warning signs for Inborn Errors of Immunity among the evaluated hospitalized pediatric patients was 8.8%, being more common in female patients, in the 5-10 years age group, and presenting one episode of severe systemic infection. It is expected that these results will contribute to the early detection and proper management of PIDs.