1. Repositório Institucional da Universidade Federal de Sergipe - RI/UFS
  2. PRODUÇÃO CIENTÍFICA
  3. DOD - Departamento de Odontologia (São Cristóvão)
  4. DOD - Artigos de periódicos
Por favor, use este identificador para citar o enlazar este ítem: https://ri.ufs.br/jspui/handle/riufs/24212
Registro completo de metadatos
Campo DC Valor Lengua/Idioma
dc.contributor.authorCarli, João Paulo de-
dc.contributor.authorSilva, Soluete Oliveira da-
dc.contributor.authorLinden, Maria Salete Sandini-
dc.contributor.authorBusin, Carmen Silvia-
dc.contributor.authorParanhos, Luiz Renato-
dc.contributor.authorSouza, Paulo Henrique Couto-
dc.date.accessioned2026-01-13T20:36:17Z-
dc.date.available2026-01-13T20:36:17Z-
dc.date.issued2014-
dc.identifier.citationCARLI, J. P. et al. Evaluation of cellular proliferative activity in patients with oral lichen planus and hepatitis C through AgNOR method. Brazilian Dental Journal, Ribeirão Preto, v. 25, n. 6, p. 461-465, 2014. Disponível em: https://www.scielo.br/j/bdj/a/Cy4TfwNPsjB3xMdwSM34xLd/?lang=en. Acesso em: 13 jan. 2026.pt_BR
dc.identifier.issn0103-6440-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/24212-
dc.languageengpt_BR
dc.publisherFundação Odontológica de Ribeirão Pretopt_BR
dc.relation.ispartofBrazilian Dental Journalpt_BR
dc.subjectHepatitis Ceng
dc.subjectLichen planuseng
dc.subjectCell nucleoluseng
dc.subjectCell proliferationeng
dc.titleEvaluation of cellular proliferative activity in patients with oral lichen planus and hepatitis C through AgNOR methodpt_BR
dc.typeTesept_BR
dc.identifier.licenseCreative Commons Atribuição-NãoComercial 3.0 Não Adaptada (CC BY-NC 3.0)pt_BR
dc.description.resumoThe objective of this study was to evaluate the cellular proliferative potential of oral lichen planus (OLP) lesions from patients without hepatitis C virus (HCV) by means of AgNOR method, as well as the cellular proliferative potential of the normal oral mucosa from patients with HCV, treated or untreated by interferon and ribavirin. A cross-sectional study was developed to investigate four groups: 10 HCV+ patients without clinical signs of OLP who had never been treated for HCV infection – Group 1; 10 HCV+ patients that were under interferon and ribavirin treatment – Group 2; 15 patients with reticular OLP lesions histopathologically confirmed, without HCV – Group 3; and 15 blood donors without HCV infection and no clinical signs of OLP GROUP 4 Control Group. The cytological material of all groups was collected by the liquid-based cytology technique. Then, the sedimented material from each patient was filled with the Nucleolar Organizer Regions impregnation by silver method (AgNOR). The count of NORs was performed on 100 epithelial cell nuclei per patient using the Image Tool™ software. The Tukey HSD test was used to compare the median value of NORs among the groups and showed that the oral mucosa of HCV+ patients previously treated with anti-HCV drugs (GROUP 2), presented a higher average number of NORs in relation to others (p<0.05). The anti-HCV treatment may be related to increased cell proliferation of oral mucosa, indicating a possible relationship between OLP and HCV+ patients treated with interferon and ribavirin.pt_BR
dc.description.localRibeirão Pretopt_BR
Aparece en las colecciones: DOD - Artigos de periódicos

Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
CellularProliferativeActivityOralLichenPlanus.pdf208,17 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro sencillo del ítem


Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.