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dc.contributor.authorMelo, Mônica Santos de-
dc.contributor.authorQuintans, Jullyana de Souza Siqueira-
dc.contributor.authorAraújo, Adriano Antunes de Souza-
dc.contributor.authorDuarte, Marcelo Cavalcante-
dc.contributor.authorBonjardim, Leonardo Rigoldi-
dc.contributor.authorNogueira, Paulo Cesar de Lima-
dc.contributor.authorMoraes, Valéria Regina de Souza-
dc.contributor.authorAraújo-Júnior, João Xavier de-
dc.contributor.authorRibeiro, Êurica Adélia Nogueira-
dc.contributor.authorQuintans-Júnior, Lucindo José-
dc.date.accessioned2026-01-16T19:42:11Z-
dc.date.available2026-01-16T19:42:11Z-
dc.date.issued2014-
dc.identifier.citationMELO, M. S. et al. A systematic review for anti-inflammatory property of clusiaceae family: a preclinical approach. Evidence-Based Complementary and Alternative Medicine, v. 2014, 2014. Disponível em: https://onlinelibrary.wiley.com/doi/10.1155/2014/960258. Acesso em: 16 jan. 2026.pt_BR
dc.identifier.issn1741-4288-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/24285-
dc.languageengpt_BR
dc.publisherHindawi Publishing Corporationpt_BR
dc.relation.ispartofEvidence-Based Complementary and Alternative Medicinept_BR
dc.subjectClusiaceae familypor
dc.subjectEthnomedicinepor
dc.titleA systematic review for anti-inflammatory property of clusiaceae family: a preclinical approachpt_BR
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição 3.0 Não Adaptada (CC BY 3.0)pt_BR
dc.description.resumoBackground. Clusiaceae family (sensu lato) is extensively used in ethnomedicine for treating a number of disease conditions whichinclude cancer, inflammation, and infection. The aim of this review is to report the pharmacological potential of plants of Clusiaceaefamily with the anti-inflammatory activity in animal experiments. Methods. A systematic review about experiments investigatinganti-inflammatory activity of Clusiaceae family was carried out by searching bibliographic databases such as Medline, Scopus andEmbase. In this update, the search terms were “anti-inflammatory agents,” “Clusiaceae,” and “animals, laboratory.” Results. A totalof 255 publications with plants this family were identified. From the initial 255 studies, a total of 21 studies were selected for thefinal analysis. Studies with genera Allanblackia, Clusia, Garcinia or Rheedia, and Hypericum showed significant anti-inflammatoryactivity. The findings include a decrease of total leukocytes, a number of neutrophils, total protein concentration, granulomaformation, and paw or ear edema formation. Other interesting findings included decreased of the MPO activity, and inflammatorymediators such as NF-kB and iNOS expression, PGE2 and Il-1b levels and a decrease in chronic inflammation. Conclusion. The datareported suggests the anti-inflammatory effect potential of Clusiaceae family in animal experiments.pt_BR
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