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Use este identificador para citar ou linkar para este item: https://ri.ufs.br/jspui/handle/riufs/25058
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dc.contributor.authorFaro, Gustavo Baptista de Almeida-
dc.contributor.authorMenezes Neto, Osvaldo Alves-
dc.contributor.authorBatista, Geodete Santos-
dc.contributor.authorSilva Neto, Antônio Pereira-
dc.contributor.authorCipolotti, Rosana-
dc.date.accessioned2026-07-06T17:50:03Z-
dc.date.available2026-07-06T17:50:03Z-
dc.date.issued2015-
dc.identifier.citationFARO, G. B. A. et al. Left ventricular hypertrophy in children, adolescents and young adults with sickle cell anemia. Revista Brasileira de Hematologia e Hemoterapia, São Paulo, v. 37, n. 5, 2015. Disponível em: https://www.sciencedirect.com/science/article/pii/S1516848415001073?via%3Dihub. Acesso em: 23 mar. 2026.pt_BR
dc.identifier.issn1516-8484-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/25058-
dc.languageengpt_BR
dc.publisherSociedade Brasileira de Hematologia e Hemoterapiapt_BR
dc.relation.ispartofRevista Brasileira de Hematologia e Hemoterapiapt_BR
dc.subjectSickle cell anemiaeng
dc.subjectLeft ventricular functioneng
dc.subjectLeft ventricular dysfunctioneng
dc.subjectEchocardiographyeng
dc.titleLeft ventricular hypertrophy in children, adolescents and young adults with sickle cell anemiapt_BR
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição-Não Comercial-Sem Derivações 4.0 Internacional (CC BY-NC-ND 4.0)pt_BR
dc.description.resumoObjective: The aims of this study were to estimate the frequency of left ventricular hypertrophy and to identify variables associated with this condition in under 25-year-old patients with sickle cell anemia. Methods: A cross-sectional study was performed of children, adolescents and young adults with sickle cell anemia submitted to a transthoracic Doppler echocardiography. The mass of the left ventricle was determined by the formula of Devereux et al. with correction for height, and the percentile curves of gender and age were applied. Individuals with rheumatic and congenital heart disease were excluded. The patients were divided into two groups according to the presence or absence ofleft ventricular hypertrophy and compared according to clinical, echocardiographic and laboratory variables. Results: A total of 37.6% ofthe patients had left ventricular hypertrophy in this sample. There was no difference between the groups of patients with and without hypertrophy according to pathological history or clinical characteristics, except possibly for the use of hydroxyurea, more often used in the group without left ventricular hypertrophy. Patients with left ventricular hypertrophy presented larger left atria and lower hemoglobin and hematocrit levels, reticulocyte index and a higher albumin:creatinine ratio in urine. Conclusion: Left ventricular hypertrophy was observed in more than one-third of the young patients with sickle cell anemia with this finding being inversely correlated to the hemoglobin and hematocrit levels, and reticulocyte index and directly associated to a higher albumin/creatinine ratio. It is possible that hydroxyurea had had a protective effect on the development of left ventricular hypertrophy.pt_BR
dc.description.localSão Paulopt_BR
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