Use este identificador para citar ou linkar para este item:
https://ri.ufs.br/jspui/handle/riufs/25215| Tipo de Documento: | Artigo |
| Título: | Incorporation and effects of punicic acid on muscle and adipose tissues of rats |
| Autor(es): | Melo, Illana Louise Pereira de Silva, Ana Mara de Oliveira e Carvalho, Eliane Bonifácio Teixeira de Yoshime, Luciana Tedesco Sattler, José Augusto Gasparotto Mancini-Filho, Jorge |
| Data do documento: | 2016 |
| Resumo: | Background: This study evaluated the effect of pomegranate seed oil (PSO) supplementation, rich in punicic acid (55 %/C18:3-9c,11 t,13c/CLNA), on the lipid profile and on the biochemical and oxidative parameters in the gastrocnemius muscle and adipose tissues of healthy rats. Linseed oil (LO), rich in linolenic acid (52 %/C18:3-9c12c15c/LNA) was used for comparison. Methods: Male Wistar rats (n = 56) were distributed in seven groups: control (water); LNA 1 %, 2 % and 4 % (treated with LO); CLNA 1 %, 2 % and 4 % (treated with PSO), po for 40 days. The percentages were compared to the daily feed intake. Fatty acid profile were performed by gas chromatography, antioxidant enzymes activity by spectrophotometer and the adipocytes were isolated by collagenase tissue digestion. Analysis of variance (ANOVA) was applied to check for differences between the groups (control, LNAs and CLNAs) and principal component analysis (PCA) was used to project the groups in the factor-place (PC1 vs PC2) based on the biochemical responses assessed in the study. Results: The fatty acids profile of tissues showed that the LNA percentages were higher in the animals that were fed LO. However, PA was only detected in the adipose tissues. Conjugated linoleic acid (CLA) was present in all the tissues of the animals supplemented with PSO, in a dose dependent manner, and 9c11t-CLA was the predominant isomer. Nevertheless there were no changes in the total weight gain of the animals, the weights of the tissues, and the oxidative stress parameters in the muscle. In addition, there was an increase in the size of the epididymal fat cells in the groups treated with PSO. Principal component analysis (PCA) showed that the CLNAs groups were arranged separately with a cumulative variance of 68.47 %. Conclusions: The results show that PSO can be used as a source of CLAs but that it does not cause changes in body modulation and does not interfere in the antioxidant activity of healthy rats. |
| Palavras-chave: | Conjugated linolenic acid Punicic acid Fatty acid profile Oxidative status |
| ISSN: | 1476-511X |
| Parte de : | Lipids in Health and Disease |
| Idioma: | eng |
| Instituição/Editora: | BioMed Central |
| Citação: | MELO, I. L. P. et al. Incorporation and effects of punicic acid on muscle and adipose tissues of rats. Lipids in Health and Disease, London, v. 15, n. 40, 2016. Disponível em: https://link.springer.com/article/10.1186/s12944-016-0214-7. Acesso em: 11 jun. 2026. |
| Licença: | Creative Commons Atribuição 4.0 Internacional (CC BY 4.0) |
| Identificador: | https://doi.org/10.1186/s12944-016-0214-7 |
| URI: | https://ri.ufs.br/jspui/handle/riufs/25215 |
| Aparece nas coleções: | DNUT - Artigos de periódicos |
Arquivos associados a este item:
| Arquivo | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| IncorporationEffectsPunicicAcidMuscle.pdf | 730,32 kB | Adobe PDF |  Visualizar/Abrir |
Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.