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Please use this identifier to cite or link to this item: https://ri.ufs.br/jspui/handle/riufs/25578
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dc.contributor.authorParisi, Maria Candida R.-
dc.contributor.authorMoura Neto, Arnaldo-
dc.contributor.authorMenezes, Fabio H.-
dc.contributor.authorGomes, Marilia Brito-
dc.contributor.authorTeixeira, Rodrigo Martins-
dc.contributor.authorOliveira, José Egídio Paulo de-
dc.contributor.authorPereira, Joana Rodrigues Dantas-
dc.contributor.authorFonseca, Reine Marie Chaves-
dc.contributor.authorGuedes, Lorena Barreto Arruda-
dc.contributor.authorCosta e Forti, Adriana-
dc.contributor.authorOliveira, Ana Mayra Andrade de-
dc.contributor.authorNóbrega, Marta Barreto de Medeiros-
dc.contributor.authorColares, Víctor Nóbrega Quintas-
dc.contributor.authorSchmid, Helena-
dc.contributor.authorNienov, Otto Henrique-
dc.contributor.authorNery, Marcia-
dc.contributor.authorFernandes, Túlio Diniz-
dc.contributor.authorPedrosa, Hermelinda C.-
dc.contributor.authorOliveira, Cristina da S. Schreiber de-
dc.contributor.authorRonsoni, Marcelo-
dc.contributor.authorRezende, Karla Freire-
dc.contributor.authorQuilici, Maria Teresa Verrone-
dc.contributor.authorVieira, Alexandre Eduardo Franzin-
dc.contributor.authorMacedo, Geisa Maria Campos de-
dc.contributor.authorStuchi‑Perez, Eliana Gabas-
dc.contributor.authorDinhane, Kandir Genésio Innocenti-
dc.contributor.authorPace, Ana Emilia-
dc.contributor.authorFreitas, Maria Cristina Foss de-
dc.contributor.authorCalsolari, Maria Regina-
dc.contributor.authorSaad, Mario José Abdalla-
dc.date.accessioned2026-07-16T20:56:32Z-
dc.date.available2026-07-16T20:56:32Z-
dc.date.issued2016-
dc.identifier.citationPARISI, M. C. R. et al. Baseline characteristics and risk factors for ulcer, amputation and severe neuropathy in diabetic foot at risk: the BRAZUPA study. Diabetology & Metabolic Syndrome, London, v. 8, n. 25, 2016. Disponível em: https://link.springer.com/article/10.1186/s13098-016-0126-8. Acesso em: 16 jul. 2026.pt_BR
dc.identifier.issn1758-5996-
dc.identifier.issnhttps://doi.org/10.1186/s13098-016-0126-8-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/25578-
dc.languageengpt_BR
dc.publisherBioMed Centralpt_BR
dc.relation.ispartofDiabetology & Metabolic Syndromept_BR
dc.subjectDiabeteseng
dc.subjectRisk factors for ulcereng
dc.subjectAmputationeng
dc.subjectSevere neuropathyeng
dc.subjectBrazileng
dc.titleBaseline characteristics and risk factors for ulcer, amputation and severe neuropathy in diabetic foot at risk: the BRAZUPA studypt_BR
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição 4.0 Internacional (CC BY 4.0)pt_BR
dc.description.resumoBackground: Studies on diabetic foot and its complications involving a significant and representative sample of patients in South American countries are scarce. The main objective of this study was to acquire clinical and epide‑ miological data on a large cohort of diabetic patients from 19 centers from Brazil and focus on factors that could be associated with the risk of ulcer and amputation. Methods: This study presents cross sectional, baseline results of the BRAZUPA Study. A total of 1455 patients were included. Parameters recorded included age, gender, ethnicity, diabetes and comorbidity-related records, previous ulcer or amputation, clinical symptomatic score, foot classification and microvascular complications. Results: Patients with ulcer had longer disease duration (17.2 ± 9.9 vs. 13.2 ± 9.4 years; p < 0.001), and poorer gly‑ cemic control (HbA1c 9.23 ± 2.03 vs. 8.35 ± 1.99; p < 0.001). Independent risk factors for ulcer were male gender (OR 1.71; 95 % CI 1.2–3.7), smoking (OR 1.78; 95 % CI 1.09–2.89), neuroischemic foot (OR 20.34; 95 % CI 9.31–44.38), region of origin (higher risk for those from developed regions, OR 2.39; 95 % CI 1.47–3.87), presence of retinopathy (OR 1.68; 95 % CI 1.08–2.62) and absence of vibratory sensation (OR 7.95; 95 % CI 4.65–13.59). Risk factors for amputation were male gender (OR 2.12; 95 % CI 1.2–3.73), type 2 diabetes (OR 3.33; 95 % CI 1.01–11.1), foot at risk classification (higher risk for ischemic foot, OR 19.63; 95 % CI 3.43–112.5), hypertension (lower risk, OR 0.3; 95 % CI 0.14–0.63), region of origin (South/Southeast, OR 2.2; 95 % CI 1.1–4.42), previous history of ulcer (OR 9.66; 95 % CI 4.67–19.98) and altered vibratory sensation (OR 3.46; 95 % CI 1.64–7.33). There was no association between either outcome and ethnicity. Conclusions: Ulcer and amputation rates were high. Age at presentation was low and patients with ulcer presented a higher prevalence of neuropathy compared to ischemic foot at risk. Ischemic disease was more associated with amputations. Ethnical differences were not of great importance in a miscegenated population.pt_BR
dc.description.localLondonpt_BR
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