Atividade antimicrobiana e potencial citotóxico de agentes cimentantes voltados para a odontologia restauradora – uma revisão de literatura

Abstract

The longevity of dental restorations and rehabilitations is directly related to the appropriate choice of materials used, including cementing agents. The main function of these materials is to promote retention and sealing between the tooth structure and restorative devices, ensuring mechanical stability and marginal sealing. However, cementation failures can favor bacterial infiltration, leading to the development of secondary caries, pulp inflammation, and even periodontal compromise. In this context, the antimicrobial activity of cementing agents becomes a relevant factor, as it can help control residual microbiota and prevent infections. Several cementing agents are used in clinical practice, each with specific chemical characteristics and properties. Studies show that materials capable of releasing ions, such as fluoride or hydroxide, have greater antimicrobial potential. Therefore, understanding the antimicrobial properties and cytotoxic potential of these materials is essential for safer clinical decision-making. In this study, we will review the scientific literature on some properties of cementing agents used in restorative dentistry, analyzing their antimicrobial mechanisms of action against cariogenic microorganisms and their cytotoxic potential in the pulp. The literature review was conducted using scientific websites with articles available in the following databases: PubMed, LILACS, BVSsalud, SciELO, and Google School.