A síndrome nefrótica e sua repercussão no âmbito comportamental infantil

Abstract

Background: The nephrotic syndrome (NS) has been linked to behavioral changes, whether due to therapy with corticosteroids or inherent to its chronicity. This study was undertaken to investigate behavioral changes in children with NS and its factors associated, concerning or not to its clinical spectrum. Methods: The study included patients aged 4-18 years, being 33 patients with NS, and two groups consisting of 33 children with sickle cell anemia (SCA)and 37 individuals without chronic disease. The Child Behavior Checklist/4-18 years was administered to their caregivers. Results: When comparing all groups, patients with NS had higher prevalence of anxiety / depression (p = 0.0001) and thought problems (p = 0.01), while those with SCA had higher rates of somatic complaints (p = 0.004) and social withdrawal (p = 0.002).However, the significance of these findings is strengthened due to the disparity of means when comparing individuals without chronic disease with each sick group respectively; this fact was not observed when comparing the two sick groups. Conclusions: Chronic illness itself exerts a strong intervention on behavioral scope and the NS, up becoming as such, needs more allusive appreciation that mitigate their effects in quality of the patient life.