Alterações neurológicas do ZIKA VÍRUS na gestação: uma revisão sistemática

Abstract

Zika virus (ZIKV) is currently a global concern, especially in the Northeast of Brazil, where a higher prevalence of microcephaly associated with the virus was detected. To minimize the consequences caused by ZIKV infection, it is necessary to recognize, among other factors, brain malformations caused by it. This article is proposed to conduct a systematic review of studies which have identified the neurological changes suggested by neuroimaging fetuses or newborns whose mothers were infected by Zika virus during pregnancy. The methodology used was PICO strategy (Patient, Intervention, Comparison and Outcome). The descriptors suggested by DeCs and Mesh were used, the descriptors, in turn, were inserted in the Pubmed database which provided 116 articles of which 11 were selected after the inclusion and exclusion criteria. The results found that the most prevalent neurological disorders are microcephaly, intracranial calcifications, ventriculomegaly and lissencephaly. The importance of these findings should alert neurologists, pediatricians, physical therapists and other professionals and, above all, the health authorities to develop management strategies that minimize the clinical consequences caused by congenital infection Zica virus.