Please use this identifier to cite or link to this item:
https://ri.ufs.br/jspui/handle/riufs/23838| Document Type: | Artigo |
| Title: | Panitumumab‑induced acneiform rash in a patient with metastatic colon adenocarcinoma |
| Authors: | Martins Filho, Paulo Ricardo Saquete Kameo, Simone Yuriko Mascarenhas‑Oliveira, Ana Carolina Vieira, Nivaldo Farias Peixoto, André Luis de Santana |
| Issue Date: | Apr-2013 |
| Resumo : | Human epidermal growth factor receptor (HER1/EGFR) is a transmembrane glycoprotein of the tyrosine kinase growth factor family that is dysregulated in many solid tumors and correlated with increased metastasis, reduced survival, and poor prognosis. Panitumumab is a fully human immunoglobulin G2 monoclonal antibody that binds specifically to the EGFR with promising results for the treatment of metastatic colorectal cancer when used as monotherapy or when added to standard chemotherapeutic regimens. Despite the favorable toxicity and safety profiles, several adverse events have been reported, including gastrointestinal disorders, metabolism and nutritional disorders, and mild to moderate dermatologic toxicities. In this correspondence, we describe a case of panitumumab-induced acneiform rash in a patient with metastatic colon adenocarcinoma. |
| Keywords: | Panitumumab-induced acneiform rash Chemotherapeutic regimens Metastatic colon adenocarcinoma Dermatology |
| ISSN: | 1998-3611 |
| Is part of: | Indian Journal of Dermatology |
| Language: | eng |
| Publisher / Institution : | Medknow Publications |
| Citation: | MARTINS FILHO, P. R. S. et al. Panitumumab‑induced acneiform rash in a patient with metastatic colon adenocarcinoma. Indian Journal of Dermatology, Mumbai, v. 58, n. 2, mar./abr. 2013. Disponível em: https://journals.lww.com/ijd/fulltext/2013/58020/panitumumab_induced_acneiform_rash_in_a_patient.62.aspx. Acesso em: 12 nov. 2025. |
| License: | Creative Commons Atribuição-NãoComercial-CompartilhaIgual 4.0 Internacional (CC BY-NC-SA 4.0) |
| URI: | https://ri.ufs.br/jspui/handle/riufs/23838 |
| Appears in Collections: | DESL - Artigos de periódicos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| PanitumumabInducedAcneiformRash.pdf | 694,25 kB | Adobe PDF |  View/Open |
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