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Tipo de Documento: Artigo
Título : Panitumumab‑induced acneiform rash in a patient with metastatic colon adenocarcinoma
Autor : Martins Filho, Paulo Ricardo Saquete
Kameo, Simone Yuriko
Mascarenhas‑Oliveira, Ana Carolina
Vieira, Nivaldo Farias
Peixoto, André Luis de Santana
Fecha de publicación : abr-2013
Resumen: Human epidermal growth factor receptor (HER1/EGFR) is a transmembrane glycoprotein of the tyrosine kinase growth factor family that is dysregulated in many solid tumors and correlated with increased metastasis, reduced survival, and poor prognosis. Panitumumab is a fully human immunoglobulin G2 monoclonal antibody that binds specifically to the EGFR with promising results for the treatment of metastatic colorectal cancer when used as monotherapy or when added to standard chemotherapeutic regimens. Despite the favorable toxicity and safety profiles, several adverse events have been reported, including gastrointestinal disorders, metabolism and nutritional disorders, and mild to moderate dermatologic toxicities. In this correspondence, we describe a case of panitumumab-induced acneiform rash in a patient with metastatic colon adenocarcinoma.
Palabras clave : Panitumumab-induced acneiform rash
Chemotherapeutic regimens
Metastatic colon adenocarcinoma
Dermatology
ISSN : 1998-3611
Es parte de: Indian Journal of Dermatology
Idioma : eng
Institución / Editorial : Medknow Publications
Citación : MARTINS FILHO, P. R. S. et al. Panitumumab‑induced acneiform rash in a patient with metastatic colon adenocarcinoma. Indian Journal of Dermatology, Mumbai, v. 58, n. 2, mar./abr. 2013. Disponível em: https://journals.lww.com/ijd/fulltext/2013/58020/panitumumab_induced_acneiform_rash_in_a_patient.62.aspx. Acesso em: 12 nov. 2025.
License: Creative Commons Atribuição-NãoComercial-CompartilhaIgual 4.0 Internacional (CC BY-NC-SA 4.0)
URI : https://ri.ufs.br/jspui/handle/riufs/23838
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