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https://ri.ufs.br/jspui/handle/riufs/24756| Document Type: | Artigo |
| Title: | Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy |
| Authors: | Nascimento, Marismar Fernandes do Almeida, Bernadeth Moda de Cunha, John Lennon Silva Valois, Rafael Barreto Vieira Pinheiro, Juliana Campos Ribeiro, Maria Amália Gonzaga Lima, Sonia Oliveira Albuquerque Júnior, Ricardo Luiz Cavalcanti de |
| Issue Date: | 2015 |
| Resumo : | PURPOSE: To investigate the effect of low-level laser therapy on bone healing in diabetic rats. METHODS: Bone cavities (19 mm diameter) were performed in the femur of 72 alloxan-induced diabetic rats, which were assigned into four groups: CTR (non-diabetic control), DBT (diabetic) CTRL (non-diabetic irradiated) and DBTL (diabetic irradiated). Low-level laser therapy was performed every 48h for seven days. Animals were euthanized at seven, 18 and 30 days. Alkaline phosphatase serum levels and bone repair were analyzed. RESULTS: Low-level laser therapy significantly increased alkaline phosphatase in at seven and 18 days (p<0.001), and improved bone healing at seven (p<0.01), 18 (p<0.05) and 30 (p<0.01) in diabetic animals. In addition, bone healing in irradiated diabetic group was statistically similar to control group at 30 days (p>0.05). CONCLUSION: Low-level laser therapy increased the serum levels of alkaline phosphatase and improved bone healing in alloxaninduced diabetic rats. |
| Keywords: | Low-level laser therapy Experimental diabetes mellitus Osteogenesis Alkaline phosphatase Rats |
| ISSN: | 1678-2674 |
| Is part of: | Acta Cirúrgica Brasileira |
| Language: | eng |
| Publisher / Institution : | Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
| Citation: | NASCIMENTO, M. F. et al. Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy. Acta Cirúrgica Brasileira, São Paulo, v. 30, n. 10, p. 660–667, 2015. Disponível em: https://www.scielo.br/j/acb/a/4hswQxTgbsTL6VVdYpVVcwL/?lang=en. Acesso em: 12 mar. 2026. |
| License: | Creative Commons Atribuição 4.0 Internacional (CC BY 4.0) |
| Identifier: | https://doi.org/10.1590/S0102-865020150100000002 |
| URI: | https://ri.ufs.br/jspui/handle/riufs/24756 |
| Appears in Collections: | DOD - Artigos de periódicos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| ImprovementBoneRepairDiabeticRats.pdf | 992,75 kB | Adobe PDF |  View/Open |
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