Use este identificador para citar ou linkar para este item: https://ri.ufs.br/jspui/handle/riufs/24756
Tipo de Documento: Artigo
Título: Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy
Autor(es): Nascimento, Marismar Fernandes do
Almeida, Bernadeth Moda de
Cunha, John Lennon Silva
Valois, Rafael Barreto Vieira
Pinheiro, Juliana Campos
Ribeiro, Maria Amália Gonzaga
Lima, Sonia Oliveira
Albuquerque Júnior, Ricardo Luiz Cavalcanti de
Data do documento: 2015
Resumo: PURPOSE: To investigate the effect of low-level laser therapy on bone healing in diabetic rats. METHODS: Bone cavities (19 mm diameter) were performed in the femur of 72 alloxan-induced diabetic rats, which were assigned into four groups: CTR (non-diabetic control), DBT (diabetic) CTRL (non-diabetic irradiated) and DBTL (diabetic irradiated). Low-level laser therapy was performed every 48h for seven days. Animals were euthanized at seven, 18 and 30 days. Alkaline phosphatase serum levels and bone repair were analyzed. RESULTS: Low-level laser therapy significantly increased alkaline phosphatase in at seven and 18 days (p<0.001), and improved bone healing at seven (p<0.01), 18 (p<0.05) and 30 (p<0.01) in diabetic animals. In addition, bone healing in irradiated diabetic group was statistically similar to control group at 30 days (p>0.05). CONCLUSION: Low-level laser therapy increased the serum levels of alkaline phosphatase and improved bone healing in alloxaninduced diabetic rats.
Palavras-chave: Low-level laser therapy
Experimental diabetes mellitus
Osteogenesis
Alkaline phosphatase
Rats
ISSN: 1678-2674
Parte de : Acta Cirúrgica Brasileira
Idioma: eng
Instituição/Editora: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
Citação: NASCIMENTO, M. F. et al. Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy. Acta Cirúrgica Brasileira, São Paulo, v. 30, n. 10, p. 660–667, 2015. Disponível em: https://www.scielo.br/j/acb/a/4hswQxTgbsTL6VVdYpVVcwL/?lang=en. Acesso em: 12 mar. 2026.
Licença: Creative Commons Atribuição 4.0 Internacional (CC BY 4.0)
Identificador: https://doi.org/10.1590/S0102-865020150100000002
URI: https://ri.ufs.br/jspui/handle/riufs/24756
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