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Document Type: Artigo
Title: Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa
Authors: Dias, Antônio Santos
Silva, Déborah Soares Bispo Santos
Barboza, Benhur
Garcia, Anuska Conde Fagundes Soares
Oliveira, Betejane de
Estevam, Charles dos Santos
Araújo Neto, Vitor
Santos, André Luiz Lima Menezes dos
Scher, Ricardo
Pantaleao, Silmara de Moraes
Issue Date: Apr-2013
Abstract: Erythrina velutina Willd., Fabaceae, is a medicinal plant that can be found in the tropics and subtropics, including in the semi-arid northeastern Brazil. It is commonly used in folk medicine to treat anxiety, agitation and insomnia. E. velutina has been known to present analgesic, anti-infl ammatory and antibacterial activities, however, it is unknown if this plant present a protective effect on DNA. We assessed the antigenotoxic effect of E. velutina against the genotoxic effects induced by MMS in the root meristem cells of Allium cepa. Three concentrations of the aqueous extract (100, 200 and 400 mg/L) of this medicinal plant were used in three different types of treatment (pre-, post- and simultaneous). The effects of the extracts on the root meristem cells of A. cepa were analyzed at both macroscopic and microscopic levels. Protective effects were observed at higher concentrations in pre-treatment and in simultaneous treatment. The results suggest that E. velutina may present antigenotoxic properties and demonstrate its chemopreventive potential.
Keywords: Ansiedade
Erythrina velutina Willd
ISSN: 0102-695X
Publisher / Institution : Sociedade Brasileira de Farmacognosia
Citation: SILVA, D. S. B. S. et. al. Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa. Revista Brasileira de Farmacognosia, Curitiba, v. 23, n. 2, mar./abr. 2013. Disponível em: <>. Acesso em: 29 jan. 2015.
License: Creative Commons Attribution License
Appears in Collections:DFS - Artigos de periódicos

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