Desenvolvimento do método da desoxirribose para avaliação do potencial antioxidante dos extratos de plantas do Nordeste

Abstract

Over time, human civilization has been using natural products as the primary treatment of health needs, especially in developing countries. Today, science has the folk medicine as a driver for scientific research. Research in several areas of scientific knowledge has increasingly shown the beneficial potential of plants in preventing, reducing symptoms and curing diseases. Extracts, fractions and organic compounds from secondary plant metabolism have varied biological activities. In this context, the antioxidant potential has gained prominence in recent times due to the discovery of the damage caused to organisms by oxidative stress. This work aimed to adapt the methodology of the 2-deoxyribose antioxidant assay using gallic acid and extracts of the plant species Anadenanthera colubrina and Capparis jacobinea for mapping the antioxidant activity of extracts and fractions in the Biotechnology and Natural Product Chemistry Laboratory. Although the results are not conclusive due to the interruption of experimental work due to the pandemic, it was found the methodology was successfully adapted as the reproducibility of the analysis was verified, considering the absorbance values of the 3 repetitions for each sample were, in general, similar.