Please use this identifier to cite or link to this item: http://ri.ufs.br/jspui/handle/riufs/1971
Document Type: Artigo
Title: Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis
Other Titles: Longa duração de epilepsia e envolvimento de múltiplos lobos são fatores preditivos de pior controle das crises convulsivas em pacientes com epilepsia refratária do lobo temporal associada a neurocisticercose
Authors: Meguins, Lucas Crociati
Adry, Rodrigo Antonio Rocha da Cruz
Silva Junior, Sebastião Carlos da
Pereira, Carlos Umberto
Oliveira, Jean Goncalves de
Morais, Dionei Freitas de
Araujo Filho, Gerardo Maria de
Marques, Lúcia Helena Neves
Issue Date: Dec-2015
Abstract: Objective: To investigate the surgical outcomes of temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) and neurocysticercosis (NCC). Methods: A retrospective investigation of patients with TLE-HS was conducted in a tertiary center. Results: Seventy-nine (62.2%), 37 (29.1%), 6 (4.7%), and 5 (3.9%) patients were Engel class I, II, III, and IV, respectively. Fifty-two (71.2%) patients with epilepsy durations ≤ 10 years prior to surgery were seizure-free 1 year after the operation compared to 27 (50.0%) patients with epilepsy durations > 10 years (p = 0.0121). Forty-three (72.9%) patients with three or fewer lobes affected by NCC were seizure-free one year after the operation, and 36 (52.9%) patients with more than three involved lobes were seizure-free after surgery (p = 0.0163). Conclusions: Longer epilepsy durations and multiple lobe involvement predicted worse seizure outcomes in TLE-HS plus NCC patients._________________________________________________________________________________________ RESUMO: Objetivo: Investigar o resultado cirúrgico da epilepsia do lobo temporal associada à esclerose hipocampal (TLE-HS) e neurocisticercose (NCC). Métodos: Estudo retrospectivo realizado em um centro de epilepsia. Resultados: Cinqüenta e dois pacientes (71,2%) com 10 anos ou menos de epilepsia antes da cirurgia tornaram-se livres de crises após um ano da operação, enquanto que 27 (50,0%) com mais de dez anos tornaram-se livres de crises após a cirurgia (p = 0,0121). Quarenta e três pacientes (72,9%), com três ou menos lobos afetados pela NCC tornaram-se livres de crises após um ano de operação, enquanto que 36 pacientes (52,9%) com mais de três lobos envolvidos estavam livres de crises após a cirurgia (p = 0,0163). Conclusão: A duração mais longa da epilepsia e o envolvimento de múltiplos lobos prevê pior resultado após a cirurgia para TLE-HS mais NCC.
Keywords: Temporal lobe epilepsy
Hippocampal sclerosis
Neurocysticercosis
Epilepsia do lobo temporal
Esclerose hipocampal
Neurocisticercose
ISSN: 1678-4227
Publisher / Institution : Academia Brasileira de Neurologia - ABNEURO
Citation: MEGUINS, L. C. et al. Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 12, p. 1014-1018, dez. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001201014>. Acesso em: 23 fev. 2017.
License: Creative Commons Atribuição 4.0 Internacional
URI: https://ri.ufs.br/handle/riufs/1971
Appears in Collections:DME - Artigos de periódicos

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