Triagem neonatal para hemoglobinopatias: resultados em cinco anos de uma coorte a partir do diagnóstico pelo teste do pezinho em Sergipe

Abstract

Objective: Congenital hypothyroidism is one of the most important preventable causes of mental retardation and therefore its early diagnosis is fundamental. The objective of this study is to evaluate the effectiveness of the Neonatal Screening Program for Congenital Hypothyroidism in Sergipe in the year 2015. Methods: This is a retrospective analytical study, which evaluates the coverage of the program, main times and ages in the different stages, incidence of Congenital Hypothyroidism, age of onset of treatment. We used the IBM SPSS version 21.0 program for statistical analysis and the Microsoft Excel version 2010 program for table construction. Results: The coverage of the program in 2015 was 83.36%. Half of the neonates had their sample collection on filter paper between the third and fifth day of life, with a mean age of 5.1 days. The mean age at treatment initiation of 42.3 days and the incidence of confirmed congenital hypothyroidism in the year 2015 was 1: 2195. Conclusions: This study demonstrates the improvement of the main effectiveness indexes of the Sergipe Neonatal Screening Program in 2015, when compared to the years between 2004 and 2010. Monitoring the indices on an ongoing basis is essential for designing the necessary interventions to achieve the goals and improve the effectiveness of the program.