Hipomineralização molar-incisivo e níveis séricos de Vitamina D: uma revisão integrativa

Abstract

Molar-incisor hypomineralization (MIH) is a dental condition characterized by abnormal enamel formation of permanent molars and incisors, leading to less mineralized teeth and, consequently, more susceptible to caries and hypersensitivity. Current literature suggests that vitamin D plays an important role in the mineralization of tooth enamel and that its concentrations may be associated with molar-incisor hypomineralization (MIH). This integrative review aimed to investigate the possible relationship between molar-incisor hypomineralization and serum vitamin D levels. Electronic searches were carried out in the PubMed, Science Direct, Cochrane Reviews and Google Scholar databases in April 2024. The inclusion criteria covered articles published in Portuguese, English and Spanish, including clinical trials, observational studies, systematic reviews and meta-analyses. Fifty-two studies were identified and, after removing duplicates and applying the eligibility criteria, eight articles were included in this review. The analysis reveals that, although there is a suggested correlation between MIH and low levels of vitamin D, the data obtained are heterogeneous and lack conclusive consensus, which highlights the need for further research to confirm this causal relationship and better understand the mechanisms involved.