Infecção de corrente sanguínea em um hospital terciário

Abstract

Rationale: The peripheral blood culture is an important tool for the diagnosis and treatment of bloodstream infections, through the responsible pathogen isolation and guiding the use of antibiotics with antibiotic susceptibility, respectively. Objectives: To determine the most frequent microorganisms, the clinical significance and the susceptibility profile to antimicrobial agents obtained in blood cultures at a teaching hospital. Methods: This was a retrospective study through the analysis of positive blood cultures at the University Hospital of the Federal University of Sergipe in the period 2012 to 2014. Results: Of the 111 blood cultures obtained, the most isolated microorganisms were: Staphylococcus epidermidis (27.4%), other coagulase- negative Staphylococcus (32.7%) and Staphylococcus aureus (13.3%). Approximately half of blood cultures represented pseudobacteremia and coagulase- negative Staphylococcus was the contaminant in 89.1% of cases. Most Staphylococcus aureus strains showed susceptibility to oxacillin (66.7%), while coagulase-negative Staphylococcus resistance exhibited. No positive gram was resistant to vancomycin. Escherichia coli, other members of the Enterobacteriaceae (except Klebsiella pneumoniae) and gram negative bacilli non-fermenters were resistant to ampicillin+sulbactam, gentamicin and cefepime, respectively. Conclusions: Gram-positive accounted for most of the bacteria isolated and all were susceptible to vancomycin. The high number of contaminants can be attributed to inadequate antisepsis in the collection, as coagulase-negative Staphylococcus, more frequent contaminant is present in the skin microbiota.