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Por favor, use este identificador para citar o enlazar este ítem: https://ri.ufs.br/jspui/handle/riufs/23113
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dc.contributor.authorOliveira, David Moraes de-
dc.contributor.authorSilveira, Márcia Maria Ferreira da-
dc.contributor.authorAndrade, Emanuel Sávio de Souza-
dc.contributor.authorSobral, Ana Paula Veras-
dc.contributor.authorMartins Filho, Paulo Ricardo Saquete-
dc.date.accessioned2025-09-15T17:03:32Z-
dc.date.available2025-09-15T17:03:32Z-
dc.date.issued2011-06-
dc.identifier.citationOLIVEIRA, D. M. et al. Immunohistochemical analysis of Proliferating Cell Nuclear Antigen (PCNA) in dental follicles of impacted third molars. International Journal of Morphology, Temuco, v. 29, n. 2, p. 526-531, jun. 2011. Disponível em: https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000200037&lng=en&nrm=iso&tlng=en. Acesso em: 15 set. 2025.pt_BR
dc.identifier.issn0717-9502-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/23113-
dc.languageengpt_BR
dc.publisherSociedad Chilena de Anatomíapt_BR
dc.relation.ispartofInternational Journal of Morphologypt_BR
dc.subjectImmunohistochemistryeng
dc.subjectDental sacpor
dc.subjectThird molareng
dc.titleImmunohistochemical analysis of Proliferating Cell Nuclear Antigen (PCNA) in dental follicles of impacted third molarspt_BR
dc.title.alternativeAnálisis imunohistoquímico de Antígeno de Proliferación Celular Nuclear (PCNA) en folículos dentales de los terceros molares retenidosspa
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0)pt_BR
dc.description.resumo: This study investigated the immunodetection of PCNA in epithelial components of dental follicles associated with impacted third molars without radiographical and morphological signs of pathosis. A total of 105 specimens of dental follicles associated with impacted third molars with incomplete rhizogenesis (between Nolla’s stage 6 and 9) were surgically removed from 56 patients. Epithelial cell proliferating was determined by using immunohistochemical labeling. Statistical analysis was performed using the Fisher exact test. Of the 105 dental follicles collected, 6 were PCNA-positive (≈ 6%). The specimens with squamous metaplasia and epithelial hyperplasia had higher rates of positivity for PCNA, as well as those with proliferative remnants of odontogenic epithelium. In conclusion, this study shows that dental follicles at this stage of development have low proliferative potential, but suggests that squamous metaplasia, hyperplasia of the epithelial lining and presence of proliferative odontogenic epithelial rests in the connective tissue may be early signs of developing lesions of odontogenic origin.pt_BR
dc.description.localTemucopt_BR
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