Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, state of Sergipe, Brazil

Lemos, Lígia Mara Dolce de; Rocha, Thaísa Fonseca Siqueira; Conceição, Marcos Vinícius da; Silva, Eduardo de Lemos; Santos, Alessandro Henrique da Silva; Gurgel, Ricardo Queiroz

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Campo DC	Valor	Lengua/Idioma
dc.contributor.author	Lemos, Lígia Mara Dolce de	-
dc.contributor.author	Rocha, Thaísa Fonseca Siqueira	-
dc.contributor.author	Conceição, Marcos Vinícius da	-
dc.contributor.author	Silva, Eduardo de Lemos	-
dc.contributor.author	Santos, Alessandro Henrique da Silva	-
dc.contributor.author	Gurgel, Ricardo Queiroz	-
dc.date.accessioned	2025-09-26T18:37:47Z	-
dc.date.available	2025-09-26T18:37:47Z	-
dc.date.issued	2012-12	-
dc.identifier.citation	LEMOS, L. M. D. et al. Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, state of Sergipe, Brazil, Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 46, n. 6, p. 682-686, nov./dez. 2012. Disponível em: https://www.scielo.br/j/rsbmt/a/RfTHVPBrsv3M3MhcKFvVPTs/?lang=en. Acesso em: 26 set. 2025.	pt_BR
dc.identifier.issn	1678-9849	-
dc.identifier.uri	https://ri.ufs.br/jspui/handle/riufs/23302	-
dc.language	por	pt_BR
dc.publisher	Sociedade Brasileira de Medicina Tropical - SBMT	pt_BR
dc.relation.ispartof	Revista da Sociedade Brasileira de Medicina Tropical	pt_BR
dc.subject	HIV	eng
dc.subject	Vertical transmission of infectious disease	eng
dc.subject	Zidovudine	eng
dc.subject	Post-exposure prophylaxis	eng
dc.title	Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, state of Sergipe, Brazil	pt_BR
dc.type	Artigo	pt_BR
dc.identifier.license	Creative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0)	pt_BR
dc.description.resumo	Introduction: The main route of human immunodeficiency virus (HIV) infection in children is from mother to child. The preventive measures established for the Aids Clinical Trial Group protocol 076 (ACTG 076) significantly reduces HIV vertical transmission rates. This study aims to evaluate the implementation of the ACTG 076 protocol in the maternity units of State of Sergipe, Brazilian northeast. Methods: This is a descriptive, retrospective study with a quantitative approach, with HIV positive women and children exposed, attending a Maternity reference for high-risk pregnancies. Data were obtained from patient records registered in the years 1994 to 2010. Results: Amongst the 110 pregnant women and exposed newborns, the ACTG 076 protocol was fully utilized in only 31.8% of the participants. During the prenatal period, zidovudine (ZDV) was taken by 79.1% of the pregnant women. Only 49.1% of HIV seropositive patients used ZDV during delivery. Two (1.8%) children were considered infected and 50 (45.5%) do not have a conclusive diagnosis to date. Conclusions: There were significant deficiencies in the prevention of mother-to-child transmission of HIV, including lack of compliance with the three phases of the ACTG 076 protocol; inadequacies in prenatal care; inappropriate mode of delivery and lack of adequate follow up of exposed children.	pt_BR
dc.description.local	Uberaba	pt_BR
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