1. Repositório Institucional da Universidade Federal de Sergipe - RI/UFS
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  3. DOD - Departamento de Odontologia (São Cristóvão)
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Use este identificador para citar ou linkar para este item: https://ri.ufs.br/jspui/handle/riufs/23314
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dc.contributor.authorOliveira, David Moraes de-
dc.contributor.authorSilveira, Márcia Maria Ferreira da-
dc.contributor.authorAndrade, Emanuel Sávio de Souza-
dc.contributor.authorSobral, Ana Paula Veras-
dc.contributor.authorMartins Filho, Paulo Ricardo Saquete-
dc.contributor.authorSantos, Thiago de Santana-
dc.contributor.authorOliveira, Patrícia Leimig Amorim de-
dc.contributor.authorPeixoto, Aline Carvalho-
dc.contributor.authorSantos, Jadson Alípio Santana de Souza-
dc.contributor.authorPiva, Marta Rabello-
dc.date.accessioned2025-09-29T16:24:36Z-
dc.date.available2025-09-29T16:24:36Z-
dc.date.issued2012-
dc.identifier.citationOLIVEIRA, D. M. et al. Immunohistochemical analysis of human homologue of drosophila patched (PTCH) in dental follicles of impacted third molars, International Journal of Morphology, Temuco, v. 30, n. 1, p. 105-109, 2012. Disponível em: https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100018&lng=en&nrm=iso&tlng=en. Acesso em: 29 set. 2025.pt_BR
dc.identifier.issn0717-9502-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/23314-
dc.languageengpt_BR
dc.publisherSociedad Chilena de Anatomíapt_BR
dc.relation.ispartofInternational Journal of Morphologypt_BR
dc.subjectImmunohistochemistryeng
dc.subjectDental follicleeng
dc.subjectOdontogenic epithelialeng
dc.subjectPTCHeng
dc.titleImmunohistochemical analysis of human homologue of drosophila patched (PTCH) in dental follicles of impacted third molarspt_BR
dc.title.alternativeAnálisis imunohistoquímico del homólogo humano del gen parcheado de drosofila (PTCH) en folículos dentales de terceros molares retenidoseng
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0)pt_BR
dc.description.resumoThis study investigated the immunodetection of PTCH in epithelial components of dental follicles associated with impacted third molars without radiographic signs of pathosis. One hundred and five specimens of dental follicles associated with impacted third molars with incomplete rhizogenesis (between Nolla’s stage 6 and 9) were surgically removed from 56 patients. Epithelial cell proliferation was determined by using immunohistochemical labeling. Statistical analysis was performed using Fisher exact test and a level of significance of 5%. Of the 105 dental follicles collected, 3 were PTCH-positive. The specimens with squamous metaplasia and epithelial hyperplasia had higher rates of positivity for PTCH, as well as those with active remnants of odontogenic epithelium. This study suggests that the odontogenic cells of the dental follicle might be proliferating during the rhizogenesis, while the squamous metaplasia and hyperplasia of the epithelial lining and proliferative odontogenic epithelial rests show the differentiation potential of dental follicles.pt_BR
dc.description.localTemucopt_BR
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