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Please use this identifier to cite or link to this item: https://ri.ufs.br/jspui/handle/riufs/23547
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dc.contributor.authorSilva, Dayanne Meneses-
dc.contributor.authorCosta, Emmanoel Vilaça-
dc.contributor.authorNogueira, Paulo Cesar de Lima-
dc.contributor.authorMoraes, Valéria Regina de Souza-
dc.contributor.authorCavalcanti, Sócrates Cabral de Holanda-
dc.contributor.authorSalvador, Marcos José-
dc.contributor.authorRibeiro, Luis Henrique Gonzaga-
dc.contributor.authorGadelha, Fernanda Ramos-
dc.contributor.authorBarison, Andersson-
dc.contributor.authorFerreira, Antonio Gilberto-
dc.date.accessioned2025-10-16T17:36:25Z-
dc.date.available2025-10-16T17:36:25Z-
dc.date.issued2012-
dc.identifier.citationSILVA, D. M. et al. Ent-kaurane diterpenoids and other constituents from the stem of Xylopia laevigata (Annonaceae). Química Nova, São Paulo, v. 35, n. 8, p. 1570-1576, 2012. Disponível em: https://www.scielo.br/j/qn/a/kp4NVBgm9xQWGRXBtRBn4Hj/?lang=en. Acesso em: 16 out. 2025.pt_BR
dc.identifier.issn1678-7064-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/23547-
dc.languageengpt_BR
dc.publisherSociedade Brasileira de Químicapt_BR
dc.relation.ispartofQuímica Novapt_BR
dc.subjectXylopia laevigataeng
dc.subjectEnt-kaurane-diterpeneseng
dc.subjectLarvicidal propertieseng
dc.subjectAntifungal propertieseng
dc.titleEnt-kaurane diterpenoids and other constituents from the stem of Xylopia laevigata (Annonaceae)pt_BR
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0)pt_BR
dc.description.resumoPhytochemical investigation of the hexane extract from the stem of Xylopia laevigata led to the isolation of the ent-kaurane diterpenoids, ent-kaur-16-en-19-oic acid, 4-epi-kaurenic acid, ent-16b-hydroxy-17-acetoxy-kauran-19-al, ent-3b-hydroxy-kaur-16- en-19-oic acid, and ent-16b,17-dihydroxy-kauran-19-oic acid, as well as spathulenol and a mixture of b-sitosterol, stigmasterol and campesterol. The identification of the compounds was performed on the basis of spectrometric methods including GC-MS, IR, and 1D and 2D NMR. Potent larvicidal activity against Aedes aegypti larvae with LC50 of 62.7 mg mL-1 was found for ent-3b-hydroxykaur-16-en-19-oic acid. This compound also showed significant antifungal activity against Candida glabrata and Candida dubliniensis with MIC values of 62.5 mg mL-1.pt_BR
dc.description.localSão Paulopt_BR
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DQI - Artigos de periódicos

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