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Use este identificador para citar ou linkar para este item: https://ri.ufs.br/jspui/handle/riufs/23588
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dc.contributor.authorAlmeida, Jackson Roberto Guedes da Silva-
dc.contributor.authorSouza, Grasielly Rocha-
dc.contributor.authorSilva, Juliane Cabral-
dc.contributor.authorSaraiva, Sarah Raquel Gomes de Lima-
dc.contributor.authorOliveira Júnior, Raimundo Gonçalves de-
dc.contributor.authorQuintans, Jullyana de Souza Siqueira-
dc.contributor.authorBarreto, Rosana de Souza Siqueira-
dc.contributor.authorBonjardim, Leonardo Rigoldi-
dc.contributor.authorCavalcanti, Sócrates Cabral de Holanda-
dc.contributor.authorQuintans Junior, Lucindo José-
dc.date.accessioned2025-10-21T18:25:05Z-
dc.date.available2025-10-21T18:25:05Z-
dc.date.issued2013-
dc.identifier.citationALMEIDA, J. R. G. S. et al. Borneol, a bicyclic monoterpene alcohol, reduces nociceptive behavior and inflammatory response in mice. The Scientific World Journal, New York, n. 1, 2013. Disponível em: https://onlinelibrary.wiley.com/doi/epdf/10.1155/2013/808460. Acesso em: 21 out. 2025.pt_BR
dc.identifier.issn1537-744X-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/23588-
dc.languageengpt_BR
dc.publisherHindawi Publishing Corporationpt_BR
dc.relation.ispartofThe Scientific World Journalpt_BR
dc.subjectBorneoleng
dc.subjectBicyclic monoterpeneeng
dc.subjectAntinociceptive and anti-inflammatory activitieseng
dc.titleBorneol, a bicyclic monoterpene alcohol, reduces nociceptive behavior and inflammatory response in micept_BR
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição 3.0 Não Adaptada (CC BY 3.0)pt_BR
dc.description.resumoBorneol, a bicyclic monoterpene, has been evaluated for antinociceptive and anti-inflammatory activities. Antinociceptive and anti-inflammatory activities were studied by measuring nociception by acetic acid, formalin, hot plate, and grip strength tests, while inflammation was prompted by carrageenan-induced peritonitis. The rotarod test was used to evaluate motor coordination. Borneolproduced a significant (p < 0.01) reduction of the nociceptive behavior at the early and late phases of paw licking and reducedthe writhing reflex in mice (formalin and writhing tests, resp.). When the hot plate test was conducted, borneol (in higher dose)produced an inhibition (p < 0.05) of the nociceptive behavior. Such results were unlikely to be provoked by motor abnormality. Additionally, borneol-treated mice reduced the carrageenan-induced leukocytes migration to the peritoneal cavity. Together, ourresults suggest that borneol possess significant central and peripheral antinociceptive activity; it has also anti-inflammatory activity.In addition, borneol did not impair motor coordination.pt_BR
dc.description.localNew Yorkpt_BR
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