Efeito do etodolaco pré-emptivo na sensibilidade trans e pós-operatória provocada por clareamento dental: estudo clínico randomizado

Abstract

The aim of this study was to evaluate the efficacy of Etodolac preemptive on tooth sensitivity caused by in-office bleaching. Thirty four patients were selected to receive two sessions of tooth bleaching. One hour prior to each session, they received a capsule containing placebo and Etodolac, while in the second session they received a different treatment from the first one (cross-over design). The sequence of treatment was randomized previously to beginning of study. The initial evaluation of sensitivity was performed using a visual analogue scale (VAS) and a verbal rating scale (VRS). The bleaching procedure was carried out with hydrogen peroxide gel (35% Whiteness HP Blue, FGM, Joinville, SC, Brazil) for 45 minutes. The sensitivity was evaluated during the procedure (20’ and 40’), immediately after and 24 hours after the bleaching. The absolute risk and relative risk, for each session, were calculated and the differences between percentage of absolute risk compared using the McNemar test. The intensity level of sensitivity between treatment was compared using the Mann-Whitney test (p <0.05). There were no significant differences between the treatments in any evaluation moment. In conclusion, the preemptive use of Etodolac was no effective to reduce the risk or level of trans and post-treatment sensitivity caused by tooth bleaching.